亚甲兰注射治疗椎间盘源性腰痛的临床观察  

Intradiscal methylene blue injection for treatment of discogenic low back pain

作　　者：杨洪[1] 高春华[1] 庞晓东[1] 李端明[1] 彭宝淦[1] 

机构地区：[1]武警总医院脊柱外科,北京100039

出　　处：《脊柱外科杂志》2012年第5期271-273,共3页Journal of Spinal Surgery

摘　　要：目的选择一组符合行腰椎融合手术标准的慢性失能性椎间盘源性腰痛患者,给予腰椎椎间盘内注射亚甲蓝,观察其临床效果。方法回顾性分析2010年8月～2011年12月行亚甲蓝椎间盘内注射治疗的90例椎间盘源性腰痛病例。用疼痛视觉模拟量表(visual analog scale,VAS)评分和Oswestry功能障碍指数(Oswestry disability index,ODI)评估每个患者手术前后的腰痛情况和腰椎功能,以评价亚甲蓝注射疗效。结果患者术后随访时间为3～6个月。所有患者中,83例(92.2%)腰痛症状有明显改善或完全消失,80例(88.9%)腰椎功能明显改善。手术前后的VAS评分和ODI比较,差异具有统计学意义(P<0.01)。结论椎间盘内注射亚甲蓝是一种非常有效的治疗椎间盘源性腰痛的方法。Objective To observe the clinical efficacy of intradiscal methylene blue injection for the treatment of patients with discogenic low back pain in conformity with the criteria for interbody fusion surgery.Methods A total of 90 discogenic low back pain cases treated by intradiscal methylene blue injection from August 2010 to December 2011 were involved in this retrospective research.The efficacy of methylene blue injection was assessed by visual analogue scale（VAS）for low back pain,and the Oswestry disability index（ODI） for functional recovery.Results All patients were followed up from 3 to 6 months.The disappearance or marked alleviation of low back pain were obtained in 83 patients（92.2%）,and the definite physical function improvement in 80 patients（88.9%）.The clinically meaningful improvement on the ODI and the VAS scores were obtained in the patients with chronic discogenic low backpain after treatment and the differences were statistically significant（P0.01）.Conclusion The injection of methylene blue into the painful intervertebral disc may be a very effective method for the treatment of chronic discogenic low back pain.

关 键 词：椎间盘 腰痛 亚甲蓝 注射 

分 类 号：R681.533.1[医药卫生—骨科学]