大黄对脂质过氧化物——丙二醛的影响  

Observation on Effect of Rhubarb on Lipid Peroxides-Malondialdehyde in Vitro

作　　者：郭昌燕[1] 张宁宁[1] 陈玲[1] 赵淑颖[1] 王宝恩[1] 

机构地区：[1]首都医科大学附属北京友谊医院,北京100050

出　　处：《贵阳医学院学报》2000年第2期135-136,共2页Journal of Guiyang Medical College

摘　　要：应用富含脂质过氧化物丙二醛 (MDA)的鼠肝与中药大黄孵育 ,观察药物对MDA的影响。结果显示 ,大黄对MDA呈明显抑制作用 ,且抑制作用有明显的量效关系。提示临床应用大黄可以抑制MDA生成过多 ,从而减轻组织器官损伤、防止病情恶化。The effect of Rhubarb on lipid peroxides malondialdehyde(MDA) was studied by incubating Rhubarb with rat liver containing a lot of MDA. The results showed that Rhubarb had obvious inhibition on MDA and this effect correlated to the dose of Rhubarb. It suggested that Rhubarb could inhibite the production of MDA, thus reduced the injury of the tissues and organs therefore prevented the patient's condition from deterioration.

关 键 词：大黄属 脂质过氧化作用 丙二醛 中药 

分 类 号：R285.5[医药卫生—中药学]