肾综合征出血热患者血小板四项参数动态变化及意义  

The Change of Four Parameters in Platelet in Hemorrhagic Fever with Renal Syndrome and Its Significance

作　　者：杜宇[1] 叶晓光[1] 唐正运[1] 李贵华[1] 

机构地区：[1]广州医学院第二附属医院传染科,广州510260

出　　处：《现代临床医学生物工程学杂志》2000年第2期28-29,共2页Journal of Modern Clinical Medical Bioengineering

摘　　要：目的　进一步了解肾综合征出血热 (HFRS)患者血小板四项参数的动态变化和临床表现的关系 .　方法采用SysmexK - 10 0 0型自动血细胞计数仪对 47例HFRS患者血小板四项参数进行动态检测 .结果　HFRS患者在发热期、低血压休克期和少尿期血小板计数 (PLT)、平均血小板体积 (MPV)和血小板压积 (PCT)均明显降低 .临床上有多个部位出血表现的患者 ,其MPV和PCT比仅有皮肤粘膜出血点的患者显著降低 .至恢复期 ,上述三项指标均恢复到正常水平 .结论　动态监测HFRS患者血小板四项参数的变化对了解患者血小板功能状态及估计患者出血倾向的严重程度有一定的临床意义 .Objective To further investigate the change of the four parameters in platelet.Methods we detected the platelet count(PLT), mean platelet volume(MPV), platelet distribution width(PDW) and plateletcrit(PCT) in 47 patients with hemorrhagic fever with renal syndrome dynamically.Results The results showed that PLT,MPV and PCT were significantly reduced in febile phase, hypotensiveshock phase and oliguria phase.In the patients with multiple situs hemorrhage, the MPV and PCT were more significantly reduced than thois in patients with skin or mucous hemorrhage only.In convalescence, the level of PLT, MPV and PCT all returned to normal.Conclusions The results indicated that dynamic measurement of PLT, MPV and PCT might be valuable in indirectly reflecting the situation of platelet function and estimating the degree of hemorrhage in HFRS.

关 键 词：肾综合征出血热 血小板 参数 

分 类 号：R512.8[医药卫生—内科学]