通脉活血灵胶囊对实验性高脂血症家兔血脂及动脉粥样硬化的影响  

Effect of Tongmaihuoxueling Capsule on Blood Lipid and Atherosclerosis in Hyperlipidemic Rabbits

作　　者：李兰芳[1] 张建新[1] 兰漫野 刘赤平[1] 陈素青[1] 徐涛[1] 陈灵燕 

机构地区：[1]河北省医学科学院,石家庄050021 [2]河北省中医学院

出　　处：《中草药》2000年第6期440-442,共3页Chinese Traditional and Herbal Drugs

摘　　要：观察通脉活血灵胶囊对实验性高脂血症家兔血脂调节变化和动脉粥样硬化形成的影响。实验结果表明 ,高脂饲料喂养家兔可导致高脂血症 ,并可诱发动脉粥样硬化 (AS)。通脉活血灵胶囊 2 .4,1.2 g/ kg组均可明显降低血清总胆固醇、血清甘油三酯、血清低密度脂蛋白 ,可升高血清高密度脂蛋白 ;并明显抑制 AS形成和发展 。To study the effect of Tongmaihuoxueling Capsule (TMHXL) on blood lipid and atherosclerosis Hyperlipidemic rabbit models were prepared by feeding high lipid diet for 12 weeks High, medium and low doses of TMHXL were fed thereafter Their blood lipid levels were messured at the 12th week The aorta was isolated and stained with sudan Ⅲ and hematoxylin eosin to examine the gross and microscopic evidences of atherosclerosis TMHXL could decrease the serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL C) content, but elevate the high density lipoprotein cholesterol (HDL C) and prevent the formation of atherosclerosis TMHXL is effective for the prevention of hyperlipidemia and the development of atherosclerosis

关 键 词：通脉活血灵 动脉粥样硬化 高脂血症 中医药疗法 

分 类 号：R259.435[医药卫生—中西医结合] R259.892[医药卫生—中医内科学]