反社会人格障碍患者说谎的功能磁共振分析  

Functional MRI analysis of deception among people with antisocial personality disorders

作　　者：蒋伟雄[1,2,3] 廖坚[2] 刘华生[1,2] 唐艳[1,2] 王维[1,2] 

机构地区：[1]中南大学生物医学工程研究所,长沙410083 [2]中南大学湘雅三医院放射科,长沙410013 [3]湖南第一师范学院信息科学与工程系,长沙410205

出　　处：《中南大学学报（医学版）》2012年第11期1141-1146,共6页Journal of Central South University ：Medical Science

基　　金：中南大学基础研究基金(394201067;);湖南第一师范学院科研基金(XYS09N13)~~

摘　　要：目的:研究反社会人格的罪犯说谎时的功能磁共振情况。方法:对32个满足反社会人格标准的男性罪犯进行功能磁共振,分析他们在说真话和说假话时的脑区激活差异以及习惯性说谎程度与激活脑区强弱之间的关系。结果:反社会人格障碍患者左扣带回前部,双侧的背外侧前额叶,左顶下小叶与其欺骗行为的执行相关。并且随着善于说谎程度的加强,这些区域的激活强度呈下降趋势。结论:利用大脑的血氧水平依赖激活可对反社会人格障碍患者说谎和说真话行为进行识别,但是血氧水平依赖激活差异会随着善于说谎程度的增加而降低,这对测谎精确度提出了挑战。Objective： To investigate the functional magnetic resonance imaging （fMRI） data of deception in antisocial personality disorders （ASPD）. Methods： A total of 32 criminals meeting the criteria for ASPD underwent fMRI at 1.ST while responding truthfully questions or lying. We compared the brain activities between truth-telling and lie-teUing, and then computed the correlation coefficient between the contrast brain activities and the inclination to deception. Results： The left anterior cingulate gyms, the bilateral dorsohteral prefrontal cortex, and left inferior parietal lobule were associated with the executive aspects of deception among people with ASPD. But with the greater in clmation to deception, the blood oxygen level dependent （BOLD） activities in those regions decreased. Conclusion： Evaluations of truthful and untruthful communications pertaining to ASPD subjects may be differentiated in terms of brain BOLD activities, though those activities may decrease in habitual liars, which remains a challenge to the diagnostic accuracy in lie detection.

关 键 词：反社会人格障碍 功能磁共振 欺骗 测谎 强迫选择任务 

分 类 号：R445.2[医药卫生—影像医学与核医学]