LATHYROIDES, Encoding a WUSCHEL-Related Homeoboxl Transcription Factor, Controls Organ Lateral Growth, and Regulates Tendril and Dorsal Petal Identities in Garden Pea （Pisum sativum L.）  

作　　者：Li-Li Zhuang Mike Ambrose Catherine Rameau Lin Weng Jun Yang Xiao-He Hu Da Luo Xin Li 

机构地区：[1]School of Life Science and Biotechnology,Shanghai Jiao Tong University,Shanghai 200240,China [2]Department of Crop Genetics,John Innes Centre,Colney,Norwich NR47UH,UK [3]Station de Genetique et d'Amelioration des Plantes,Institut J.P.Bourgin,UR 254 INRA,Versailles,France [4]National Key Laboratory of Plant Molecular Genetics,Institute of Plant Physiology and Ecology,Shanghai Institutes for Biological Sciences,ChineseAcademy of Sciences,Shanghai 200032,China [5]State Key Laboratory of Biocontrol,School of Life Sciences,Sun Yat-Sen University,135 West Xin-gang Road,Guangzhou 510275,China

出　　处：《Molecular Plant》2012年第6期1333-1345,共13页分子植物（英文版）

基　　金：National Natural Science Foundation of China，Science and Technology Planning Project of Guangdong Province,China

摘　　要：During organ development, many key regulators have been identified in plant genomes, which play a conserved role among plant species to control the organ identities and/or determine the organ size and shape. It is intriguing whether these key regulators can acquire diverse function and be integrated into different molecular pathways among different species, giving rise to the immense diversity of organ forms in nature. In this study, we have characterized and cloned LATHYROIDES （LATH）, a classical locus in pea, whose mutation displays pleiotropic alteration of lateral growth of organs and predominant effects on tendril and dorsal petal development. LATH encodes a WUSCHEL-related home- oboxl （WOX1） transcription factor, which has a conserved function in determining organ lateral growth among different plant species. Furthermore, we showed that LATH regulated the expression level of TENDRIL-LESS （TL）, a key factor in the control of tendril development in compound leaf, and LATH genetically interacted with LOBED STANDARD （LST）, a floral dorsal factor, to affect the dorsal petal identity. Thus, LATH plays multiple roles during organ development in pea： it maintains a conserved function controlling organ lateral outgrowth, and modulates organ identities in compound leaf and zygomorphic flower development, respectively. Our data indicated that a key regulator can play important roles in different aspects of organ development and dedicate to the complexity of the molecular mechanism in the control of organ development so as to create distinct organ forms in different species.During organ development, many key regulators have been identified in plant genomes, which play a conserved role among plant species to control the organ identities and/or determine the organ size and shape. It is intriguing whether these key regulators can acquire diverse function and be integrated into different molecular pathways among different species, giving rise to the immense diversity of organ forms in nature. In this study, we have characterized and cloned LATHYROIDES （LATH）, a classical locus in pea, whose mutation displays pleiotropic alteration of lateral growth of organs and predominant effects on tendril and dorsal petal development. LATH encodes a WUSCHEL-related home- oboxl （WOX1） transcription factor, which has a conserved function in determining organ lateral growth among different plant species. Furthermore, we showed that LATH regulated the expression level of TENDRIL-LESS （TL）, a key factor in the control of tendril development in compound leaf, and LATH genetically interacted with LOBED STANDARD （LST）, a floral dorsal factor, to affect the dorsal petal identity. Thus, LATH plays multiple roles during organ development in pea： it maintains a conserved function controlling organ lateral outgrowth, and modulates organ identities in compound leaf and zygomorphic flower development, respectively. Our data indicated that a key regulator can play important roles in different aspects of organ development and dedicate to the complexity of the molecular mechanism in the control of organ development so as to create distinct organ forms in different species.

关 键 词：PEA LATH LST TL lateral growth organ identity. 

分 类 号：Q945.48[生物学—植物学] P618.130.2[天文地球—矿床学]