幽门螺杆菌相关性消化道溃疡合并出血的危险因素Logistic回归分析  

Logistic regression analysis of risk factors of Helicobacter pylori associated peptic ulcer complicated with hemorrhage

作　　者：刘彦娥[1] 国建真 田力[1] 

机构地区：[1]河北省衡水市第五人民医院消化内科,河北衡水053000

出　　处：《海南医学院学报》2012年第12期1718-1720,共3页Journal of Hainan Medical University

基　　金：中国高校医学期刊临床专项资金项目(112210426)~~

摘　　要：目的:了解幽门螺杆菌相关性消化道溃疡合并出血的相关影响因素,通过Logistic回归分析,探究相关的危险性因素,为相关的预防策略的制定提供依据。方法:收集临床诊断为幽门螺杆菌相关性消化道溃疡的病例180例,统计其中合并出血的病例数,并通过调查问卷的设计,对可能的相关影响因素进行调查,经Logistic回归分析,确定相应的危险性因素。结果:180例幽门螺杆菌相关性消化道溃疡中,合并出血的病例为68例,占37.78%。经Logistic回归分析结果显示:嗜酒(OR=3.43,P<0.05)、工作压力大(OR=2.22,P<0.05)、睡眠差(OR=1.45,P<0.05)、食用非甾体消炎药如布洛芬(OR=3.45,P<0.05)、辛辣饮食(OR=1.69,P<0.05)、不按时三餐进食(OR=1.54,P<0.05)等构成幽门螺杆菌相关性消化道溃疡合并出血的危险因素。结论:幽门螺杆菌相关性消化道溃疡合并出血的发生率较高,相关的危险因素较多,临床上应及时给予必要的预防策略,预防出血的发生。Objective： To explore factors affecting the occurence of Helicobacter pylorirelated in peptic ulcer complicated with hemorrhage.Methods： A total of 180 cases with Helicobacter pylori associated peptic ulcer complicated with hemorrhage were selected.Through the design of questionnaire,the possible related factors were investigated,and risk factors were identified by logistic regression analysis.Results： There were 68 cases had complication of hemorrhage accounting for 37.78%.Logistic regression analysis showed alcoholics（OR=3.43,P0.05）,high working pressure（OR=2.22,P0.05）,poor sleep quality（OR=1.45,P0.05）,consumption of NSAIDs such as ibuprofen（OR=3.45,P0.05）,hot and spicy diet（OR=1.69,P0.05）,irregular diet（OR=1.54,P0.05） were risk factors of Helicobacter pylori related peptic ulcer complicated with hemorrhage.Conclusions： The incidence of Helicobacter pylori associated peptic ulcer complicated with hemorrhage is high,and its occurence is associated with various risk factors.Preventive strategies against hemorrhage are necessary.

关 键 词：幽门螺杆菌 消化道溃疡 消化道出血 危险因素 LOGISTIC回归分析 

分 类 号：R632.1[医药卫生—外科学]