2005～2010年某院金黄色葡萄球菌流行病学分析  

The prevalence of Staphylococcus aureus from 2005 to 2010 in a hospital

作　　者：瞿小英[1] 王美堂[1] 何建[1] 

机构地区：[1]第二军医大学附属长海医院急诊科,上海200433

出　　处：《重庆医学》2012年第33期3519-3520,3523,共3页Chongqing medicine

摘　　要：目的了解该院金黄色葡萄球菌(SA)临床分布及其耐药情况。方法回顾分析该院2005年1月至2010年12月1 715例感染SA患者,采用稀释法得出的药敏结果及其感染患者的相关临床资料。结果 2005～2010年检出的SA中耐甲氧西林金黄色葡萄球菌(MRSA)的构成比为62.8%～76.9%;MRSA感染者的平均年龄较高;含有SA的标本主要来源于痰液和伤口分泌物;MRSA的科室分布前5位为脑外科、烧伤科、急诊科、神经内科、普通门诊;MRSA耐药率大于90%的药物分别为苯唑西林、青霉素、四环素和庆大霉素;未发现利奈唑胺、万古霉素耐药SA。结论 MRSA感染情况比较严重,应加强对SA耐药性的监测,并根据药敏试验结果合理使用抗菌药物。Objective To investigate the distribution and antimicrobial resistance characteristics of Staphylococcus aureus（SA）.Methods The drug-sensitivity data of SA and relevant clinical data from 1 715 cases in our Hospital from Jan 2005 to Dec 2010 were retrospectively analyzed.Results The composition of methicillin-resistant Staphylococcus aureus（MRSA） from 2005 to 2010 was 62.8%-76.9%.The average age of patients with MRSA was high.Specimens containing SA were mainly from sputum and wound secretions.The top five sections with distribution of MRSA were brain surgery department,burn unit,emergency department,neurology department,out-patient department.The resistance rate of MRSA greater than 90% of the antibiotics were oxacillin,penicillin,tetracycline and gentamicin resistance.SA resisting linezolid or vancomycin was not found.Conclusion The infection of MRSA was in serious condition.The aged was risk factor to MRSA infection.It is necessary to strengthen the monitoring of the SA antibiotics resistance and the rational use of antibiotics basing on the results of susceptibility tests.

关 键 词：葡萄球菌 金黄色 耐药性 流行病学研究 

分 类 号：R446.5[医药卫生—诊断学] R181.3[医药卫生—临床医学]