2009～2011年某院抗菌药物使用及细菌耐药性分析  

Analysis of use of anti-bacterial agents and bacterial drug resistance from 2009 to 2011 in a hospital

作　　者：汪华蓉[1] 方伟[1] 郭虎[1] 黄道秋[1] 

机构地区：[1]重庆三峡中心医院药学部,404000

出　　处：《重庆医学》2012年第33期3521-3523,共3页Chongqing medicine

摘　　要：目的了解该院抗菌药物应用及细菌耐药情况,为临床合理应用抗菌药物提供参考。方法收集该院2009～2011年抗菌药物使用资料,并对用药频度(DDDs)、销售金额、药品用量以及检出细菌耐药的变化情况进行分析。结果该院抗菌药物DDDs变化较大,注射用左氧氟沙星使用量明显上升。注射头孢噻肟使用量明显下降,抗菌药物销售金额呈现先上涨后下降趋势。检出的常见细菌的耐药情况越来越严重。结论抗菌药物使用合理性有一定的改善,但仍需进一步提高。Objective To investigate the use of anti-bacterial agents and the bacterial drug resistance so as to provide evidence for rational use of anti-bacterial.Methods The data about the use of anti-bacterial agents between 2009 and 2011 were collected for analysis of DDDs,consumption sum,consumption amount and the change in bacterial drug resistance.Results DDDs of anti-bacterial agents showed a great change,with that of injection of Levofloxacin increasing obviously.On the contrary,DDDs of injection of cefotaxime decreased markedly.The consumption sum of anti-bacterial agents increased initially and decreased later.The drug resistance of common bacteria became increasingly serious.Conclusion The use of anti-bacterial agents tends to be more rational than before,but it remains to be improved further.

关 键 词：抗菌药 用药频度 药物耐受性 

分 类 号：R446.5[医药卫生—诊断学]