1,1'-二茂铁二羧酸二辛酯的合成方法研究  

Research on Synthesis Methods of Dioctyl 1,1'-Ferrocenedicarboxylate

作　　者：何宜丰 聂教荣 俞艳[2] 李慧[2] 李晓强[2] 杨军[2] 

机构地区：[1]国营江河化工厂,湖北远安444200 [2]中国科学院上海有机化学研究所,上海200032

出　　处：《化学推进剂与高分子材料》2012年第6期54-57,共4页Chemical Propellants & Polymeric Materials

基　　金：国家自然科学基金资助(批准号:20802088;91017006;90917017)

摘　　要：对1,1'-二茂铁二羧酸二辛酯的合成方法开展了研究。通过二茂铁的Friedel-Crafts酰基化反应合成了1,1'-二乙酰基二茂铁,然后用次氯酸钠氧化1,1'-二乙酰基二茂铁得到1,1'-二茂铁二甲酸。研究了1,1'-二茂铁二甲酸直接酯化法制备1,1'-二茂铁二甲酸二甲酯,以其为原料通过酯交换的方法可以65%的收率和四步合计48%的总收率实现1,1'-二茂铁二甲酸二辛酯的合成,产物结构用1H-NMR、IR进行了表征。The synthesis methods of dioctyl 1,1＇-ferrocenedicarboxylate were studied. The l,l＇-diacetyl ferrocene was synthesized by Friedel-Crafts acylation reaction of ferrocene. The 1,1＇-ferrocenedicarboxylic acid was prepared by subsequent oxidation of the obtained 1,1＇-diacetyl ferrocene with sodium hypochlorite. The preparation process of dimethyl 1,1＇-ferrocenedicarboxylate by using direct esterification method of 1,1＇-ferrocenedicarboxylic acid was studied. Using dimethyl 1,1＇-ferrocenedicarboxylate as raw material, the synthesis of dioctyl 1,1＇-ferrocenedicarboxylate by transesterification method can be realized with 65% yield and 48% total yield during four steps. The product structure was characterized by using 1H-NMR and IR.

关 键 词：1 1’-二茂铁羧酸酯 酯交换反应 1 1’-二茂铁二羧酸二辛酯 

分 类 号：O627.81[理学—有机化学]