高血压病患者动态血压参数及心血管病危险因素对颈动脉粥样硬化的预测价值  

Predictive value of the ambulatory blood pressue monitoring parameters and cardiovascular risk factors on carotid artery artherosclerosis in essential hypertension patients

作　　者：董建新[1] 王宝芝[1] 

机构地区：[1]嘉应学院医学院附属医院心内科,广东梅州514031

出　　处：《中国实用医刊》2012年第23期3-5,共3页Chinese Journal of Practical Medicine

基　　金：梅州市科技局立项课题（2010-B-70）

摘　　要：目的探讨高血压动态血压参数及心血管病危险因素对颈动脉粥样硬化的预测价值。方法对所有入选患者询问病史、体检并行动态血压监测、颈动脉超声及血生化检测。结果颈动脉粥样硬化组男性患者比率、平均年龄、高血压病程、吸烟者比例、尿酸、总胆固醇、低密度脂蛋白胆固醇水平高于对照组，高密度脂蛋白胆固醇水平低于对照组，24h收缩压、白昼收缩压、夜间收缩压、24h脉压、白昼脉压、夜间脉压水平、非杓型血压检出率及其他心血管病危险因素高于无颈动脉粥样硬化组（对照组），差异有统计学意义（P均〈0．05）。结论男性、年长、高血压病程、吸烟者、尿酸、血脂异常，血压昼夜节律异常、收缩压及脉压差增大以及心血管病危险因素聚集对颈动脉粥样硬化病变形成的影响更明显。Objective To investigate the predictive value of the ambulatory blood pressue monito- ring parameters and cardiovascular risk factor on carotid artery artherosclerosis in essential hypertension pa- tients. Methods All selected patients were inquired for case history and given physical examination, am- bulatory blood pressure monitoring, carotid ultrasound examination and blood biochemistry detection. Re- stilts The ratio of male patients, smoking, mean age, duration of hypertension, smokers proportion, the levels of UA, total cholesterol and low density lipoprotein cholesterol in carotid artery artherosclerosis group were higher than those in control group; and the level of high density lipoprotein cholesterol in carotid ar- tery artherosclerosis group was lower than that in control group, there were significant differences between the two groups （ P 〈 0. 05）. The levels of the 24 h SBP, dSBP, nSBP, 24 h PP, dPP, nPP and the ratio of non-dipper blood pressure in CAS group were higher than those in control group, there were significant differences （ P 〈 0. 05）. Conclusions It has more significant on the impact of carotid artery artherosclerotic lesion formation in that of male, elder, the course of hypertension, smoking, UA, dyslipidemia, non-dipper blood pressure, systolic blood pressure, pulse pressure and the gather of risk factor of cardiovascular.

关 键 词：高血压病 动态血压监测 心血管病危险因素 颈动脉粥样硬化 

分 类 号：R544[医药卫生—心血管疾病]