流动注射化学发光法测定芬布芬  

Determination of Fenbufen in Tablets by Flow Injection Chemiluminescence

作　　者：周艳梅[1] 王亚萍[1] 张君丽[1] 马同森[1] 

机构地区：[1]河南大学化学化工学院、环境与分析科学研究所,河南开封475004

出　　处：《河南大学学报（自然科学版）》2012年第6期722-724,共3页Journal of Henan University:Natural Science

摘　　要：建立了一种测定芬布芬的流动注射化学发光新方法.在1.0×10-7～9.0×10-6 g/mL范围内,高锰酸钾-甲醛体系的相对化学发光强度与芬布芬浓度呈良好的线性关系,方法的检出限为1.5×10-7 g/mL.对1.0×10-6 g/mL芬布芬平行测定11次,相对标准偏差为1.0%.本方法可应用于片剂中芬布芬的测定,结果显示回收率为94%～97%.A novel flow-injection chemiluminescence method was developed for the determination of fenbufen in this paper.The CL conditions of the system were investigated and optimized.The results indicated that the relative CL intensity was linear over the concentration of fenbufen ranging from 1.0 × 10-7 to 9.0 × 10-6 g/mL.The detection limit is 1.5 × 10-7 g/mL and the relative standard deviation is 1.0% for 11 times measurements of 1.0 × 10-6 g/mL standard solution.This method has been successfully applied to the determination of fenbufen in tablets with a recovery range of 94 %~97 %.

关 键 词：流动注射 化学发光 高锰酸钾 甲醛 芬布芬 

分 类 号：O65[理学—分析化学]