代谢综合征与脑白质疏松症的相关性研究  

Relationship between Metabolic Syndrome and Leukoaraiosis

作　　者：王龙飞[1] 苏增锋 吴晟昊[1] 程小华[1] 汪飞[1] 曹毅[1] 

机构地区：[1]安徽省黄山市人民医院神经内科,245000 [2]安徽医科大学第三附属医院干部病房

出　　处：《中国全科医学》2012年第32期3688-3690,共3页Chinese General Practice

基　　金：安徽医科大学校科学研究基金(2011xkj081)

摘　　要：目的探讨代谢综合征(MS)与脑白质疏松症(LA)的相关性。方法选取2009年1月—2012年3月黄山市人民医院神经内科住院患者216例,根据颅脑磁共振成像结果分为LA组(124例)及non-LA组(92例),分析两组MS各组分患病率及同时患有MS 3个、4个、3或4个组分的患病率。根据Fazekas量表,1、2级为LA轻中度组(74例),3级为LA重度组(50例),比较两组MS各组分患病率及患有MS 1、2、3、4个组分患病率。结果 LA组与non-LA组患者高血糖、高血压、超重和(或)肥胖、血脂紊乱及同时患有MS 3个、4个、3或4个组分的患病率比较,差异均有统计学意义(P<0.01)。LA轻中度组与LA重度组患者高血糖、高血压、超重和(或)肥胖、血脂紊乱患病率比较,差异均有统计学意义(P<0.05);两组患者患有MS 1、2、3、4个组分患病率比较,差异亦有统计学意义(u=6.09,P<0.05)。结论 MS与LA的发生关系密切,LA程度越严重,MS组分越多。Objective To explore the relationship between metabolic syndrome（MS） and Leukoaraiosis（LA）.Methods 216 patients admitted to neurology department of Huangshan People′s Hospital from January 2009 to March 2012 were divided into LA group（124 cases） and non-LA group（92 cases） according to cranial magnetic resonance findings.The frequencies of MS and frequencies of 3 MS components,4 MS components and 3 or 4 components in the two groups were then analyzed.Based on Fazekas scale,the patients were further divided into mild to moderate LA group with LA from first to second level（74 cases） and severe LA group with LA of third level（50 cases）.The frequencies of MS and frequencies of different components of MS were analyzed.Results The frequencies of high blood glucose,high blood pressure,overweight and（or） obese,dyslipidemia,frequencies of 3 MS components,4 MS components and 3 or 4 MS components between LA group and non-LA group showed statistically significant differences（P0.01）.The frequencies of high blood glucose,high blood pressure,overweight and（or） obese and dyslipidemia between mild to moderate LA group and severe LA group showed statistically significant differences（P0.05）.The frequencies of the patients suffering from 1,2,3 or 4 MS components between the two groups also showed statistically significant differences（u=6.09,P0.05）.Conclusion Metabolic syndrome and leukoaraiosis are closely related.The more components of MS the patients suffer from,the more serious the LA is.

关 键 词：代谢综合征 脑白质疏松 

分 类 号：R589[医药卫生—内分泌]