Meiotic DSBs and the control of mammalian recombination  

作　　者：Kenneth Paigen Petko Petkov 

机构地区：[1]The Jackson Laboratory,Bar Harbor.ME 04609,USA

出　　处：《Cell Research》2012年第12期1624-1626,共3页细胞研究（英文版）

摘　　要：The laboratories of Galina Petuk- hova and R Daniel Camerini-Otero have achieved significant technical advances in determining the genomewide sites of DNA double-strand breaks （DSBs） where the process of genetic exchange between chromatids during meiosis begins. Applying the new approaches to male meiosis in mice, their experimental results considerably increase our insights into the nature and regulation of these processes.

关 键 词：DNA双链断裂 减数分裂 哺乳动物 重组 控制 技术进步 基因交流 分裂过程 

分 类 号：Q691[生物学—生物物理学] Q253