早产儿脑室周围-脑室内出血影响因素分析  

Incidence of Peri-Intraventricular Haemorrhage and Its Associated Factors in Preterm Infants

作　　者：庞永红[1] 王建梅[1] 卢青[1] 邓晓毅[1] 刘松林[1] 丁玉红[1] 

机构地区：[1]江苏省徐州市妇幼保健院,江苏徐州221009

出　　处：《儿科药学杂志》2012年第12期3-5,共3页Journal of Pediatric Pharmacy

基　　金：江苏省徐州市卫生局科研课题(编号:XWJ2011049)

摘　　要：目的:探讨早产儿脑室周围-脑室内出血(peri/intraventricular hemorrhage,PIVH)的发生率及影响因素。方法:对2011年1月1日至2011年12月31日在徐州市妇幼保健院住院的1 079例早产儿于生后48～72 h做头颅B超检查,用列联表法调查早产儿PIVH发生率与胎龄、出生体重和窒息之间的关系。结果:(1)2011年全年该院早产儿PIVH发生率为63.3%,其中Ⅰ级546例(79.9%),Ⅱ级122例(17.9%),Ⅲ级15例(2.2%)。大部分病例没有临床表现。(2)随着胎龄、出生体重和Apgar评分的降低,PIVH的发生率升高(P<0.01)。34～36 w、31～33 w和28～30 w三组早产儿PIVH发生率分别为60.6%、66.7%和75.0%;体重大于2 500 g、1 500～2 500 g和小于1 500 g三组早产儿PIVH发生率分别为56.2%、65.0%和80.2%;无窒息组和轻度窒息组早产儿PIVH发生率分别为57.2%和82.0%,重度窒息组高达88.9%。结论:(1)早产儿PIVH发生率高,建议所有早产儿应早期监测头颅B超。(2)早产儿PIVH发生率与胎龄、出生体重和窒息密切相关。Objective： The aim of this study was to investigate the prevalence and potential risk factors of Peri/intraventricular hemorrhage（PIVH） in preterm infants.Methods： The studied population comprised 1,079 preterm infants treated at the Xuzhou Women and Children＇s Health Care Hospital between January 1,2011 to December 31,2011.Haemorrhage was diagnosed on the basis of repeated ultrasounds performed between the first 48 and 72 hours of life.The relation between the incidence of PIVH and obstetrical risk factors were analyzed by contingency tables.Results： The investigations showed the incidence of haemorrhages was 63.3%（683 infants）.The 546（79.9%） cases were diagnosed as PIVH I,122（17.9%） as PIVH II and 15（2.2%） as PIVH III.A large percentage of cases had no clinical manifestations.With the decreasing of the gestational age,birth weight and Apgar score,the incidence of PIVH was increased（P〈0.01）.The probability of PIVH in 34-36 weeks,31-33 weeks and 28-30 weeks preterm infants was 60.6%,66.7% and 75.0% respectively;56.2% in weight 2,500 g,65.0% in weight 1,500-2,500 g and 80.2% in weight 1,500 g;57.2% with Apgar scores 8-10 points,82.0% with 4-7 points and 88.9% with 0-3 points.Conclusions：（1） The incidence of PIVH was very high.This study suggests that ultrasound screening should be reserved to all premature infants.（2） The incidence of PIVH is related to gestational age,birth weight and perinatal asphyxia in preterm infants.

关 键 词：早产儿 脑室周围-脑室内出血 头颅B超 

分 类 号：R722.6[医药卫生—儿科]