持续性肾替代治疗对重症急性胰腺炎的疗效评价  

Effect Evaluation of the Continuous Renal Replacement Therapy in Severe Acute Pancreatitis

作　　者：张应宏[1] 夏腾飞[1] 钟文兰[1] 雷霆[1] 臧泽林[1] 尚娟[1] 

机构地区：[1]川北医学院第二临床医学院·南充市中心医院重症医学科,四川南充637000

出　　处：《西部医学》2012年第12期2271-2273,共3页Medical Journal of West China

基　　金：中美默沙东"慢性疾病"防治国际合作项目(编号:20100167)

摘　　要：目的观察持续肾替代治疗(CRRT)治疗重症急性胰腺炎(sever acute pancreatitis,SAP)的疗效,评价CRRT对SAP的干预效果。方法将52例符合中华医学会胰腺外科组的SAP诊断及分级标准的患者,随机分为A、B两组,A组行常规治疗,B组常规治疗+CRRT,对两组患者进行临床疗效对比观察。结果两组病例进入ICU时其Ranson评分,APACHEⅡ评分CTSI无统计学差异(P>0.05);经治疗后各评分及腹痛、腹胀缓解时间,住院时间、并发症发生率、治愈率均有统计学差异(P<0.05)。结论 CRRT对SAP有明显疗效。Objective To observe the efficacy of continuous renal replacement therapy on severe acute pancreatitis （SAP）, and evaluate the effect of continuous renal replacement therapy intervention in severe acute pancreatitis. Methods 52 cases of SAP patients, whose diagnosis and grading standards were according to pancreatic surgery group of the Chi- nese Medical Association, were randomly divided into two groups, group A received the routine therapy,group B received the routine therapy together with the continuous renal replacement therapy, and their Clinical efficacy were observed and analyzed. Results There was no Significant difference between the two groups among Ranson score, APACHE Ⅱ score and CTSI when they were admitted to hospital（P〉0. 05） ,and it was significantly different among the scores and the time of abdominal pain, bloating relief time, hospitalization time, incidence of complications and cure rates after they received the treatments（P〈0. 05）. Conclusion Continuous renal replacement therapy has a significant effect on severe acute pancreatitis.

关 键 词：持续性肾替代治疗 重症急性胰腺炎 疗效 

分 类 号：R657.51[医药卫生—外科学]