丹参川芎嗪联合奥扎格雷治疗老年稳定型心绞痛疗效观察  

The effect of salvia tetramethylpyrazine United ozagrel treatment with elderly with stable angina pectoris

作　　者：王雷[1] 施阳[1] 

机构地区：[1]四川省人民医院急救中心,四川成都610072

出　　处：《西部医学》2012年第12期2316-2317,2320,共3页Medical Journal of West China

摘　　要：目的观察丹参川芎嗪注射液联合奥扎格雷治疗老年稳定型心绞痛的临床疗效。方法选取2009年11月～2010年7月收治的稳定型心绞痛老年患者88例,随机分为对照组与观察组各44例,对照组在常规治疗的基础上加用奥扎格雷,观察组在常规治疗的基础上加用奥扎格雷和丹参川芎嗪;一个疗程(14天)之后比较两组临床疗效、心绞痛发作的频率及时间、心电图、C反应蛋白(CRP)、血浆纤维蛋白原(FIB)的变化。结果观察组临床症状及疗效、心电图明显优于对照组(P<0.05),心绞痛发作的频率以及时间下降则更为明显(P<0.05),FIB、CRP明显低于对照组(P<0.05)。结论丹参川芎嗪联合奥扎格雷治疗老年稳定型心绞痛能更有效地改善患者心绞痛症状。Objective To compare the efficacy of treatment of elderly with stable angina pectoris with Salvia tetramethylpyrazine United ozagrel. Methods Select stable angina in elderly patients in the Sichuan Provincial People＇s Hospital emergency medicine from November 2009 to July 2010, 88 cases were randomly divided into control and treatment groups of 44 cases. Control group is treated with ozagrel on the basis of the conventional treatment. Treatment group is treated with ozagrel and Salvia tetramethylpyrazine on the basis of the conventional treatment. After a course of treatment （14 days） compare the clinical efficacy, the frequency of angina attacks and time, electrocardiogram, C reactive protein （CRP）, plasma fibrinogen （FIB） between the two groups. Results The clinical symptoms and the efficacy and the ECG of the treatment group, was significantly better than the control group, decreased frequency of angina attacks and the time is even more obvious, FIB and CRP was significantly lower than the control group. Conclusion The clinical treatment of the elderly stable angina with the salvia tetramethylpyrazine and ozagrel is more effective in improving symptoms of patients.

关 键 词：丹参川芎嗪 奥扎格雷 稳定型心绞痛 

分 类 号：R514.4[医药卫生—内科学]