江苏省常州地区变应性鼻炎患者变应原分析  

Analysis on the allergens in allergic rhinitis patients in Changzhou district of Jiangsu

作　　者：姚聆清[1] 邱建鹤[1] 巢长江[1] 毛建军[1] 钱俊勇[2] 薛建荣[2] 周慧娟[2] 

机构地区：[1]江苏省常州市第一人民医院(苏州大学第三附属医院)耳鼻咽喉头颈外科,江苏常州213001 [2]江苏省常州市第三人民医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第23期1066-1069,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:通过江苏省常州地区变应性鼻炎(AR)患者16种标准化变应原皮肤点刺试验的结果,汇总分析出本地区AR患者的主要变应原,为AR的合理防治及流行病学提供依据。方法:对4 242例临床疑似AR的患者进行皮肤点刺试验并进行结果分析。结果:点刺试验阳性者2 638例,阳性率为62.19%;粉尘螨及户螨吸入性变应原阳性率分别以85.86%、83.55%列第1、2位,其次为蟑螂(11.49%)和葎草(9.82%),食入性变应原海虾(5.76%)列第5位,真菌(2.92%)排位靠后;各年龄段的主要变应原分布有差异;尘螨阳性等级为+++及++++的构成比在儿童组显著高于成人组(P<0.01)。结论:本地区防治AR的重点应针对主要变应原尘螨。儿童与成人变应原亦有差异。Objective：To investigate the distribution of positive allergens in patients with allergic rhinitis in Changzhou.Method：A total of 4 242 cases with allergic symptoms and signs underwent skin prick test with 16 kinds of standardized allergens.The common allergens were found out.The samples were stratified on seven age groups to analysis the distributive characteristics of allergens responsible for each group.The samples were also stratified on children group and adults group to analysis their response degree to Dust mite.Result：2 638 cases（62.19%） had the positive reaction,including male 1 380（52.3%） cases,female 1 258（47.7%） cases.Dermatophagoides farinae and Dermatophagodies pteronyssinus had the highest positive ratio（85.86%,83.55%） in inhalation group,followed cockroach（11.49%） and Humulus L.（9.82%）,fungus（2.92%） in the lower positivie ratio.Shrimp（5.76%） was the most common allergen in food group.The distribution of common allergens in different age groups was variable.There was significantly higher sensitivity to dust mite between children group compared to adults group（P0.01）.Conclusion：The study shows that Dust mite was the mostly responsible common allergen in Changzhou district.The distribution of common allergens in children group and adults group was variable.

关 键 词：鼻炎 变应性 变应原 皮肤点刺试验 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]