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机构地区:[1]厦门大学附属中山医院耳鼻咽喉科,厦门361004
出 处:《临床耳鼻咽喉头颈外科杂志》2012年第23期1092-1094,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery
摘 要:目的:探讨鼻腔上皮-肌上皮癌的病理学特点、诊断、治疗及预后。方法:对1例鼻腔上皮-肌上皮癌进行分析,光镜观察和免疫组织化学检查,并进行文献复习。结果:临床表现不具备特征性,诊断只能依靠病理检查。肿瘤主要由肌上皮细胞和腺上皮细胞等组成,免疫组织化学检测CK-L、CK-P、S-100、α-平滑肌肌动蛋白等表达阳性。结论:鼻腔上皮-肌上皮癌是一种罕见肿瘤,以手术治疗为主,有复发和远处转移的潜能。Objective:To seek pathological features,diagnosis,treatment,prognosis of Epithelial-myoepithelial carcinoma arising in the nasal cavity.Method:One case of Epithelial-myoepithelial carcinoma arising in the nasal cavity was analyzed retrospectivelyand studied with immunohistochemical Staining and light microscopy,as well as review of the literature.Result:The clinicalfeature of epithelial-myoepithelial carcinoma in the nasal cavity was atypical and diagnosis relied on pathologic features.Epithelial-myoepithelial carcinoma consisted of myoepithelial and epithelial cells.Immunohistochemical staining demonstrated that cytokeratin P,cytokeratin L,S-100 protein,a-smooth muscle actin expressed positively.Conclusion:Epithelial-myoepithelial carcinoma in the nasal cavity is a rare neoplasm.Wide surgical excision with a clear margin is the main therapy,and these tumors have the potential for metastasis andrecurrence.
分 类 号:R765[医药卫生—耳鼻咽喉科]
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