MII期卵是完全成熟的受精前卵母细胞吗?  

What does a MII oocyte mean?

作　　者：徐艳文[1] 

机构地区：[1]中山大学附属第一医院,广州510080

出　　处：《生殖医学杂志》2012年第6期543-545,共3页Journal of Reproductive Medicine

摘　　要：卵母细胞质量决定胚胎的质量。在卵母细胞发育过程中，众多环节影响卵母细胞自身发育潜能。人类卵母细胞停滞在减数分裂I期可长达几十年。在这期间，卵母细胞积聚mRNA、蛋白质、脂肪和糖等最后成熟所必须的物质。在最后阶段，卵母细胞完成减数分裂I，并进入减数分裂II的中期（MII）。卵母细胞成熟由相互关联和依赖的两部分组成：胞浆成熟和核成熟。有第一极体出现即提示核成熟。但是否MII期的卵母细胞就代表完全成熟的受精前卵母细胞？答案当然是否。可以从以下几方面对此进行分析。Oocytes play a pivotal role in the development of human embryo. Oocyte at metaphase II stage with the appearance of the 1st polar body is defined as matured oocyte. However, MII oocyte may not have fully maturated in cytoplasm, leading to the fact that most matured oocytes have limited development competence. Recent reviews showed that all parameters regarding oocyte morphology had poor predictive value. Therefore, more intensive and coordinated researches on oocyte cytoplasm maturation are needed.

关 键 词：卵母细胞 核成熟 胞浆成熟 卵母细胞形态 

分 类 号：R3[医药卫生—基础医学]