能谱CT成像对肺癌分型的初步研究  

Preliminary study of lung cancer types with gemstone spectral CT imaging

作　　者：李明英[1] 王广丽[2] 崔丁也[2] 张成琪[2] 

机构地区：[1]山东大学医学院,济南250012 [2]山东大学附属千佛山医院影像科,济南250014

出　　处：《山东大学学报（医学版）》2012年第12期73-76,共4页Journal of Shandong University:Health Sciences

基　　金：山东省科技攻关项目(2009GG10002040)

摘　　要：目的探讨能谱CT成像在肺癌分型方面的初步应用。方法选取60例首次诊断为肺癌的患者,进行宝石能谱成像(GSI)模式扫描,然后利用GSI后处理功能,分别测量肿块内同一感兴趣区的碘浓度、水浓度、能谱曲线及40 keV下的CT值,分析不同类型肺癌的能谱CT表现。结果鳞癌与腺癌的碘浓度、能谱曲线斜率及各组病例40 keV下CT值的平均值差异均有统计学意义(P<0.05),而各组之间水浓度的平均值差异无统计学意义(P>0.05)。结论能谱CT成像可对肺癌提供定性、定量的相关信息,对肺癌分型具有重要的参考价值。Objective To investigate the preliminary application of spectral CT imaging on different types of lung canc- er. Methods 60 patients who were diagnosed lung cancer at first time were scanned in gemstone spectral imaging （GSI） mode by using dual energy CT. Iodine concentration, water concentration, spectrum energy curve and CT val- ues at 40 keV in the region of interest of the mass were measured with GSI post-processing software to analysis the spec- tral feature of different types of lung cancer. Results Significant differences in iodine concentration, spectrum energy curve and CT values at 40 keV existed between lung squamous cell carcinoma and lung adenocarcinoma （ P 〈 0.05 ）, while water concentration were found no significant difference between them （P 〉 0.05）. Conclusion GSI technique may have important value in lung cancer classification by providing qualitative and quantitative informations of tumors.

关 键 词：肺肿瘤 宝石能谱成像 病理分型 碘浓度 能谱曲线 

分 类 号：R445.5[医药卫生—影像医学与核医学]