暴马子皮化学成分研究  

Chemical Constituents of Syringae Cortex

作　　者：宋光西[1] 马玲云[1] 魏锋[1] 马双成[1] 

机构地区：[1]中国食品药品检定研究院,北京100050

出　　处：《中国药学杂志》2012年第24期1979-1982,共4页Chinese Pharmaceutical Journal

基　　金：国家自然科学基金资助项目(30873356)

摘　　要：目的研究暴马子皮(Syringae Cortex)化学成分。方法利用硅胶(200～300目)、凝胶Sephadex LH-20及制备高效液相等柱色谱技术进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果分离并鉴定了12个化合物:紫丁香苷(Ⅰ),sinapyl aldehyde 4-O-β-D-glucopyranoside(Ⅱ),丁香醛(Ⅲ),松柏醛(Ⅳ),白桦脂酸(Ⅴ),橄榄苦苷(Ⅵ),oleoside dimeth-yl ester(Ⅶ),ligstroside(Ⅷ),2″-epifraxamoside(Ⅸ),β-谷甾醇(Ⅹ),正三十烷酸(Ⅺ),对羟基苯乙醇三十烷酸酯(Ⅻ)。结论化合物Ⅱ～Ⅴ,Ⅶ,Ⅸ～Ⅻ均为首次从该植物中得到。OBJECTIVE To study the chemical constituents of Syringae Cortex. METHODS The compounds were isolated and purified by silica（ 200 -300） , pre-HPLC and Sephadex LH -20 column chromatography. The structures were identified on the basis of spectral data and physiochemical properties. RESULTS Twelve compounds were isolated and identified as syringin（ I ）, sinapylal- dehyde 4-O-fl-D-glucopyranoside（ ]] ）, syringaldehyde（ m ）, coniferyl aldehyde（ IV ）, betulinic acid（ V ）, oleuroprin（ VI ）, oleoside dimethyl ester（ VII ）, figstroside （VIH）, 2＂- epifraxamoside （ IX ）, [3-sitosterol （ X ）, n-triaconatanoie acid （ XI ） and 2- （ 4-hydroxyphe- nyl）-ethyl-l-dodeeyloctadecanoate） （XII）. CONCLUSION Compounds II - V, VII and IX - XII are isolated from this plant for the first time.

关 键 词：暴马子皮 化学成分 环烯醚萜苷 结构鉴定 丁香醛 松柏醛 白桦脂酸 

分 类 号：R284[医药卫生—中药学]