RAFT一步法制备温度和pH双重响应的多孔智能水凝胶及其性能  

One-Pot Synthesis of Porous Poly (Poly(Ethylene Glycol) Methy Ether Methacrylate-co-Acrylic Acid) Hydrogels by RAFT Polymerization

作　　者：刘桂廷[1] 杨云云[1] 叶磊[1] 闫付臻[1] 徐伟[1] 冉蓉[1] 

机构地区：[1]高分子材料工程国家重点实验室,四川大学高分子科学与工程学院,四川成都610065

出　　处：《高分子材料科学与工程》2012年第12期13-16,共4页Polymer Materials Science & Engineering

基　　金：国家自然科学基金资助项目(51173121)

摘　　要：通过可逆加成-断裂链转移聚合法(RAFT)一步反应成功合成了温度和pH双重敏感的聚乙二醇甲基丙烯酸酯(OEGMA)-co-丙烯酸梳形/多孔智能水凝胶。采用扫描电镜(SEM)对水凝胶结构进行表征,结果表明,随着加入的致孔剂聚乙二醇(PEG)分子量越大、加入量越多,所得多孔水凝胶的孔径就越大、孔的数目就越多。对水凝胶进行溶胀测试,结果表明,在RAFT试剂的调控下所得凝胶的结构更均匀,因此所得凝胶的溶胀性能较好;经PEG致孔后的水凝胶,其溶胀程度和响应速率相对于致孔前都有所提高;此外OEGMA侧链PEG的长度和交联剂中间链段的长度都对凝胶的溶胀性能有显著的影响。Poly（ethylene glycol） methy ether methacrylate-co-acrylic acid porous/comb hydrogels, double sensitive to temperature and pH, were prepared by one-pot reversible addition fragmentation chain transfer （RAFT） polymerization using poly （ ethylene glycol） methy ether methacrylate （OEGMA） as thermo-sensitive monomer, acrylic acid （AA） as pH-sensitive monomer, N, N-methylene-bisa cylamide （BIS） and poly （ethylene glycol） dimethacrylateas cross-linbrs, and poly（ethylene glycol）（PEG） as pore-forming agent. The structure of the hydrogels was observed by SEM. The swelling equilibria ratio, swelling and deswelling kinetics of the hydrogels were measured. The results of SEM macrographs indicate that the pore size of the hydrogels is modulated by adjusting the molecular weight or the amount of PEG. The swelling behaviors of hydrogels reveal that the structure of hydrogels are more homogeneous under the control of RAFT agent. The swelling equilibria ratio and response rate of porous/ comb hydrogels were larger than those of comb hydrogels. The length of PEG of the poly（ethylene glycol） methy ether methacrylate and middle segment of cross-linkers effectively affect swelling behaviors of the hydrogels.

关 键 词：可逆加成 断裂链转移聚合法 梳形 多孔水凝胶 温度和pH双敏感 聚乙二醇 

分 类 号：TB381[一般工业技术—材料科学与工程]