隔药灸治疗寒凝型痛经的疗效及对PGF_(2α)、PGE_2影响  

Treatment Effect of Herb-partitioned Moxibustion for Dysmenorrhea of Cold Stagnation Type and Its Effect on PGF_(2α) and PGE_2

作　　者：姬乐[1] 陈日兰[1] 邓朋翼[2] 周丽君[2] 杜氏春草[2] 朱英[1] 

机构地区：[1]广西中医学院附属瑞康医院,南宁530011 [2]广西中医学院,南宁530011

出　　处：《上海针灸杂志》2012年第12期882-884,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：广西中医药管理局广西卫生厅中医药科技专项课题(gzzc0924);广西教育厅科研立项项目(200911LX245)

摘　　要：目的探讨隔药灸治疗寒凝型痛经的作用机制。方法把60例寒凝型痛经患者按随机数字表分为两组,每组30例,隔药灸组采用隔药灸神阙穴,西药组采用内服西药,并设正常空白组30例不作任何治疗。结果隔药灸组总有效率(96.7%)优于西药组(83.3%)(P<0.05)。隔药灸组治疗后PGF2α、PGE2与西药组比较差异有统计学意义(P<0.01)。结论隔药灸治疗寒凝型痛经的疗效机制与调节PGF2α及PGE2有关,即可降低经期外周血PGF2α含量,升高PGE2含量。Objective To explore the action mechanism of herb-partitioned moxibustion in treating dysmenorrhea due to cold stagnation. Method Sixty dysmenorrhea patients of cold stagnation type were divided into two groups based on the random number table, 30 in each group. The herb-partitioned moxibustion group was treated by herb-partitioned moxibustion at Shenque （CV8）; the Western medication group was treated by orally-taken Western medication; a blank control group of 30 cases was set up without receiving any treatment. Result The total effective rate of the herb-partitioned moxibustion group （96.7%） was significantly superior to that of the Western medication group （83.3%）（P〈0.05）. After treatment, differences between the herb-partitioned moxibustion group and the Western medication group in comparing PGF2α and PGE2 were statistically significant （P 〈0.01）. Conclusion The action mechanism of herb-partitioned moxibustion in treating dysmenorrhea of cold stagnation type is related to its regulation effect on PGF2αand PGE2, i.e. down-regulating PGF2α and up-regulating PGE2 in peripheral blood during menstrual period.

关 键 词：痛经 间接灸 隔药灸 穴 神阙 地诺前列素 地诺前列酮 

分 类 号：R246.3[医药卫生—针灸推拿学]