α-硫羰基膦酸衍生化喹唑啉酮含磷类似物的研究  

Studies of α- Thiocarbonyl Phosphonic Acid Derivative Quinazolone Analogues Containing Phosphorus

作　　者：黄君珉[1] 陈茹玉[1] 

机构地区：[1]南开大学元素有机化学研究所

出　　处：《高等学校化学学报》2000年第8期1216-1220,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金! (批准号 :2 9972 0 2 1)

摘　　要：研究了两种不同的合成路线 ,合成 1 7个新的α-硫羰基膦酸衍生化喹唑啉酮含磷类似物 2 a～ 2 q,其结构经 NMR,IR,MS和元素分析表征 .通过单晶 X射线衍射分析 ,探讨了稠杂环标题化合物的立体化学特征 ,并对其 1 ,3位取代基的氢谱磁不等价现象进行了合理解释 .初步生物活性测试结果表明 。A series of N substituted 1 methoxycarbonylmethyl 3 substituted 2,4 dioxo 1,3,2 benzodiazaphosphorin 2 carboxamides(2a_2q) have been designed and synthesized by two methods, and their structures were confirmed by elemental analysis, NMR, IR and MS. On the basis of X ray diffraction analysis, we discussed stereochemistry of the title compounds, and studied their 1H NMR magnetic nonequivalent phenomenon which agrees with the results of X ray analysis. The preliminary bioassay shows that some of the title compounds have a good plant hormone activity.

关 键 词：α-硫羰基膦酸 喹唑啉酮含磷类似物 农药 

分 类 号：TQ450.21[化学工程—农药化工]