大鼠电针镇痛的个体差异性及其与基础痛阈的关系  

THE INDIVIDUAL VARIATION OF ELECTROACUPUNCTURE ANALGESIA AND THEIR RELATIONSHIP WITH BASAL PAIN THRESHOLD IN RATS

作　　者：刘苏星[1] 罗非[2] 沈上[2] 于英心[2] 韩济生[2] 

机构地区：[1]包头医学院生理教研室,014010 [2]北京医科大学神经科学研究所,北京100083

出　　处：《中国疼痛医学杂志》2000年第2期92-95,共4页Chinese Journal of Pain Medicine

摘　　要：电针镇痛具有个体差异性。我们采用聚类分析的统计学方法 ,以 1 0 0Hz电针30分钟内辐射热甩尾潜伏期 (TFL)升高百分数之平均值为指标 ,将 1 6 8例大鼠分为优针效和劣针效两个群体 ,其针效至少在两天之内保持相对稳定。电针镇痛效果与基础痛阈呈显著正相关。即优针效鼠的基础痛阈显著高于劣针效鼠。In the present study, we observed the individual variation of 100 Hz electroacupuncture (EA) induced analgesia in rats. EA analgesia was measured with the mean percentage increase of radiant heat induced tail flick latency within the 30 minutes stimulation period. With cluster analysis, 168 rats were allocated into two groups, namely, high responder and low responder. The effect of EA was steady in at least two days. There exists a positive correlation between the analgesic effect of EA and the basal pain threshold. The high responder rats displayed significantly higher basal pain threshold than low responders.

关 键 词：电针镇痛 个体差异性 基础痛阈 甩尾阈值 大鼠 

分 类 号：R246[医药卫生—针灸推拿学]