痒安洗液的抗炎止痒作用  

Innestigation on the anti-inflammatory and antipruritus effects of Yangan lotion in mice

作　　者：闫杏莲 卫琮玲 陈百泉 

机构地区：[1]开封医学高等专科学校第一附属医院,河南开封475001

出　　处：《中国药学杂志》2000年第6期384-385,共2页Chinese Pharmaceutical Journal

摘　　要：目的　研究痒安洗液的抗炎止痒作用。方法　采小鼠耳廓微循环实验法、二甲苯及蛋清致炎法、组胺致痒阈及体外抗菌MIC测定法观察。结果　痒安洗液可改善小鼠耳廓微循环 ,对抗小鼠耳二甲苯致炎及大鼠踝关节蛋清致炎 ,提高豚鼠组胺致痒阈及有抗菌作用。OBJECTIVE To study the anti inflammatory and antipruritus effects of Yangan lotion.METHODS The microcirculation of the mouses auricle was observed.The inflammation was caused by dimethylbenzene and albumen;The itch was caused by histamine and with extrinsis antisepsis.The MIC in vitro was also determined.RESULTS Yangan lotion improved the microcirculation of the mouses auricle,produced the anti inflammatory effects on the inflamed ear of the mouse caused by dimethylbenzene and the inflamed gymnoarthrosis of the hamster caused by albumen and relieved itching on the cavys place caused by histamine.CONCLUSION Yangan lotion had the obvious effects on dermatitis pruritus.

关 键 词：痒安洗液 抗炎 止痒 皮肤外用药 

分 类 号：R986[医药卫生—药品]