电感耦合等离子体光谱法/质谱法测定自然铜不同炮制品中砷、铅、铜、镉、汞的含量  

Determination of Elements of Cu,As,Pb,Cd and Hg in Different Pocessed Products of Pyrite

作　　者：李伟东[1] 张志杰[2] 陈逸君[3] 吴育[1] 史业东[1] 张孟群[3] 

机构地区：[1]南京中医药大学,南京210046 [2]中国中医科学院中药研究所,北京100070 [3]南京大学现代分析中心,南京210009

出　　处：《中国实验方剂学杂志》2012年第24期181-186,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家药典委员会国家药品标准提高研究课题(361388)

摘　　要：目的:建立电感耦合等离子体光谱法/质谱法(ICP-AES/MS)测定自然铜不同炮制品中砷(As)、铅(Pb)、铜(Cu)、镉(Cd)和汞(Hg)含量检测方法,为制定As,Pb,Cd,Hg等有害元素的限量标准提供依据。方法:ICP-AES/MS检测经微波消解法的供试品,通过校正曲线计算含量。结果:5种元素标准曲线线性关系良好,r=0.999 2～0.999 8,回收率符合痕量分析要求。结论:方法灵敏度高,检测限低,分析速度快,分析精密度高。Objective： To establish a method for the determination of 5 elements （As, Pb, Cu, Cd and Hg） in different pocessed products of pyrite by inductively coupled plasma atomicemission spectrometry/mass spectrometry （ICP-AES/MS） , in order to provide a basis for thelimit standards of As, Pb, Cu, Cd and Hg and other harmful elements. Method： Five elements of the digested samples were determined by ICP-AES/MS simultaneously, and the contents were calculated by calibration curves. Result： Good linearity of calibration curves was obtained for ICP-AES/MS assay, the accuracy and the recovery met the requirement of trace analysis. Conclusion： The method is highly sensitive, rapid, accuracy and offered with low LOD.

关 键 词：电感耦合等离子体光谱法 质谱法 有害元素 自然铜 煅自然铜 

分 类 号：R284.1[医药卫生—中药学]