合肥及周边地区慢性荨麻疹患者特异性IgE检测与分析  

Detection and analysis of the specific IgE in the patients with chronic urticaria in Hefei areas

作　　者：曹婷婷[1] 张成[1] 翟玉娟[1] 张洲[1] 梁波[1] 张安平[1] 

机构地区：[1]安徽医科大学第一附属医院皮肤科,合肥230022

出　　处：《安徽医学》2012年第11期1417-1419,共3页Anhui Medical Journal

基　　金：安徽省卫生厅资助课题(项目编号:2008A033)

摘　　要：目的探讨慢性荨麻疹发病与变应原的相互关系,为患者提供疾病预防的指导依据。方法采用国际标准的血清变应原特异性IgE检测试验对合肥市及周边地区846例确诊的慢性荨麻疹患者进行20种变应原的筛查。结果受检的846例慢性荨麻疹患者的变应原阳性检出率为69.26%(586例),阳性变应原中户尘螨占25.92%(152例),其阳性率最高;屋尘占18.94%(111例)列其次;其他阳性变应原依次为:腰果占7.34%(43例),矮豚草占6.31%(37例),兔毛皮屑和蟑螂各占5.97%(各35例),树花粉组合(栎、榆、梧桐、柳、三角叶杨)占4.61%(27例),狗毛皮屑3.58%(21例),芒果3.07%(18例),桑树2.60%(15例),牛奶1.88%(11例)。结论合肥市及周边地区慢性荨麻疹患者变应原以户尘螨和屋尘多见,提示患者在日常生活中应尽量避免接触阳性变应原,以降低患病率。Objective To study the association of chronic urticaria with allergens in order to provide a guiding evidence for prevention of this disease.Methods All together 846 patients with chronic urticaria were checked by the international standard method with serum specific IgE test including 20 kinds of allergen in Hefei areas.Results The tested results showed that total of the positive reaction rates reached at 69.26%（586 positive cases） in these cases.The positive rates of the house dust mites and indoor dust reached to 25.92% and 18.94% respectively,which were the first and the second in the tested allergens in this experiment.Conclusion The house dust mites and the indoor dust are perhaps the ordinary pathogenic allergens for patients with chronic urticaria in Hefei area.It is indicated that these patients be avoided to some allergens to the best of their ability in their daily life for reducing the prevalence rate.

关 键 词：慢性荨麻疹 变应原 特异性IGE检测 血清 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]