2007-2011年宁德师范学院新生HBsAg、抗-HBs和ALT检测结果分析  

Detection of HBsAg,HBsAb and ALT Among Freshmen in Ningde Normal University,2007-2011

作　　者：张朝晖[1] 张高敏[1] 李翔莺[1] 

机构地区：[1]宁德市疾病预防控制中心,福建宁德352100

出　　处：《寄生虫病与感染性疾病》2012年第4期198-200,共3页Parasitoses and Infectious Diseases

摘　　要：目的了解宁德师范学院2007-2011级新生血清乙肝表面抗原(HBsAg)、乙肝表面抗体(抗-HBs)和丙氨酸氨基转移酶(ALT)异常情况,为制定有效的乙肝预防控制措施提供科学依据。方法以宁德师范学院2007-2011级新生为检测对象,采用酶联免疫法检测HBsAg、抗-HBs,赖氏法检测ALT,严格按照试剂盒说明书进行实验操作和结果判定。结果宁德师范学院2007-2011级新生HBsAg阳性率11.08%;各年度阳性率差异无统计学意义;男生HBsAg阳性率14.09%,女生HBsAg阳性率9.79%,男生阳性率高于女生,差异有统计学意义(χ2=31.91,P<0.05)。抗-HBs阳性率43.08%,各年度阳性率差异无统计学意义,男女生阳性率差异无统计学意义。ALT异常率0.30%,各年度异常率差异无统计学意义;男生异常率高于女生,差异有统计学意义。结论 2007-2011年宁德师范学院新生HBsAg阳性率不高,但男生阳性率较高,学校应建立学生健康档案,加强健康教育,对易感人群接种乙肝疫苗,阻断并减少乙肝的传播途径。Objective To understand the status of freshmen （2007 -2011 ） with HBsAg, HBsAb and ALT in Ningde Normal University （NNU）, and to develop effective prevention and control measures towards hepatitis B. Methods Freshmen of 2007 -2011 in NNU taken as objects, method of ELISA was applied to detect HB- sAg, HBsAb ; and Reitman - Frankel＇ s method was applied to detect ALT. Results The positive rate of HB-sAg was 11.08%, and the annual positive rates were not statistically significant among years; the positive rate of males （ 14.09% ） was statistically higher than that of females （9.79%）. The positive rate of HBsAb was 43.08% , with no significant difference between male and female. The abnormal rate of ALT was 0. 30% and male＇s abnormal rate was statistically higher than that of female. Conclusion Pertinent measures including health education, establishing health file as well as vaccination should be timely taken to decrease and eliminate the prevalence of hepatitis B.

关 键 词：乙肝表面抗原 乙肝表面抗体 丙氨酸氨基转移酶 异常率 大学新生 

分 类 号：R512.62[医药卫生—内科学]