48株儿童侵袭性肺炎链球菌血清型分布  

Study on serotype distribution in 48 isolates of invasive Streptococcus pneumoniae with which children infected

作　　者：徐飞[1] 迟富丽[1] 谈华[1] 刘雪梅[1] 曹彤[1] 潘伟[1] 钟天鹰[1] 

机构地区：[1]南京医科大学附属南京儿童医院检验科,江苏南京210008

出　　处：《中国生化药物杂志》2012年第6期909-910,912,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的了解南京地区临床分离的侵袭性肺炎链球菌血清型分布情况。方法用荚膜肿胀实结果检测2007年1月-2010年12月临床分离的48株侵袭性肺炎链球菌的血清型别。结果 48株侵袭性肺炎链球菌常见的血清型别为19F(27.1%)、19A(22.8%)、14(18.7%)和9v(8.3%),有2株用丹麦抗血清无法确定血清型。结论南京地区儿童临床分离的侵袭性肺炎链球菌的常见血清型为19F、19A、14和9v,与其它地区报道有一定差别。Purpose To investigate serotype distribution of invasive Streptococcus pneumoniae of clini- cal isolates in Nanjin. Methods A total of 48 strains invasive Streptococcus pneumoniae were collected from January 2007 to December 2010. Serotyping of St＇reptococcus pneumoniae was performed by using quelling reaction. Results The most common serotypes 48 Streptococcus pneumoniae isolates were 19F （27.1%） ,19A（22.8% ） ,14（ 18.7% ） and 9v（8.3% ）. There were two strains（4.2% ） that cannot be i- dentified with the antisera used. Conclusion The major serotypes of invasive Streptococcus pneumoniae with which children infected in Nanjing are 19F, 19A,14 and 9v.

关 键 词：侵袭性肺炎链球菌 血清型 分布 儿童 

分 类 号：R446.5[医药卫生—诊断学]