胸外按压生理反馈参数的计算机仿真研究  

Computer Simulation Study on Physiological Feedback Parameters during Chest Compression

作　　者：张广[1] 郑捷文[1] 赵鹏[1] 王宇晓 钱绍文[1] 卢恒志[1] 吴太虎[1] 

机构地区：[1]军事医学科学院卫生装备研究所,天津300161 [2]天津普瑞仪器有限公司,天津300384

出　　处：《生物医学工程学杂志》2012年第6期1032-1040,共9页Journal of Biomedical Engineering

基　　金：国家高技术研究发展计划(863计划)项目资助(2009AA02Z410);国家科技支撑计划项目资助(2009BA17903)

摘　　要：模拟仿真胸外按压生理反馈参数,使急救人员从患者本身生理变化角度全面准确地了解掌握胸外按压质量,对提高心肺复苏急救培训效率和胸外按压急救水平均具有重要意义。本文基于Charles F.Babbs心肺复苏血液循环模型,建立了胸外按压关键生理反馈参数模型,对心输出量(CO)、冠脉灌注压(CPP)、呼吸末二氧化碳(PETCO2)分压和平均动脉舒张压(MARP)进行了计算机仿真。仿真结果显示,在按压频率为100次/min以上时,按压频率变化对胸外按压生理反馈参数的影响远远小于按压深度,按压深度成为影响生理反馈参数的主要因素;在按压频率和按压深度保持不变的情况下,胸泵因子与胸外按压生理反馈参数成反比。该模型能够准确模拟不同情况下的胸外按压生理反馈参数,仿真结果与动物实验结果和临床观测结果一致。To have a thorough understanding of the CPR quality based on patients various physiological states, the doctors must do something to simulate the chest compression physiological feedback parameters （CCPFP）. The CCPFP simulation plays an important role in raising efiiciency of CPR training and improving chest compression quality. In this study, the CCPFP, including cardiac output （CO）, coronary perfusion pressure （CPP）, partial pressure of End-tidal CO2 （PETCO2） and mean arterial relaxation pressure （MARP）, was simulated using Charles F. Babbs Model. Simulation results showed that the effect o[ compression depth upon CCPFP was important in the range of 2- 6cm, whereas compression rate had little effect on the CCPFP higher than 100/mira the thoracic factor is inversely proportional to the CCPFP with fixed compression depth and compression rate. The CCPFP simulation can be imple- mented at the various physiological statuses, and verified well with the animal experimental results and the clinical results.

关 键 词：胸外按压 心输出量 冠脉灌注压 呼吸末二氧化碳分压 平均动脉舒张压 

分 类 号：R459.7[医药卫生—急诊医学]