血液灌注量和破坏指标约束下的无叶片离心血泵结构优选方法的研究  

Study on Optimal Selection of Structure of Vaneless Centrifugal Blood Pump with Constraints on Blood Perfusion and on Blood Damage Indexes

作　　者：胡兆燕[1,2,3] 潘友联[1] 陈正龙[3] 张天逸[3] 路力军[1] 

机构地区：[1]上海理工大学机械工程学院,上海200093 [2]上海理工大学医疗器械与食品学院,上海200093 [3]上海医疗器械高等专科学校精密医疗器械系,上海200093

出　　处：《生物医学工程学杂志》2012年第6期1201-1206,共6页Journal of Biomedical Engineering

基　　金：上海市教委科研创新项目资助(12YZ196)

摘　　要：本文主要探索无叶片离心血泵的结构优选方法。根据临床使用要求确定优选目标;由无叶片离心血泵的结构特点制订优选方案集合;以灌注量和血液破坏程度为指标,经过两轮优选出最佳结构血泵。数值仿真结果表明可以满足设计要求,即体外循环对灌注量(压力0～380mm Hg,流量0～8L/min)、血液剪切破坏(叶轮表面剪切力不超过200Pa)和撞击破坏的要求。该结构优选方法可以快速地在方案集合中确定最佳结构方案。This paper is aimed to study the optimal selection of structure of vaneless centrifugal blood pump. The optimal objective is determined according to requirements of clinical use. Possible schemes are generally worked out based on structural feature of vaneless centrifugal blood pump. The optimal structure is selected from possible schemes with constraints on blood perfusion and blood damage indexes. Using an optimal selection method one can find the optimum structure scheme from possible schemes effectively. The results of numerical simulation of optimal blood pump showed that the method of constraints of blood perfusion and blood damage is competent for the requirements of selection of the optimal blood pumps.

关 键 词：血液灌注 血液破坏 体外循环 离心血泵 优选 

分 类 号：TH789[机械工程—仪器科学与技术]