不同人群非胰岛素依赖型糖尿病危险因素的病例对照研究  

Case-control Studies on the Risk Factors of Non-insulin Dependent Diabetes Mellitus among Different Population Groups

作　　者：赵仲堂[1] 贾存显 郝凤荣 李光荣[2] 于红岩[3] 王泰山[4] 李明信[5] 潘玉珍 于现军 

机构地区：[1]山东医科大学公共卫生学院流行病学教研室,250012 [2]滨州医学院 [3]山东省荣成市人民医院 [4]山东省莱州市人民医院 [5]山东省安丘市人民医院 [6]山东省东平县人民医院

出　　处：《预防医学文献信息》2000年第3期201-203,共3页Liferatue and Information On Preventine Medicine

基　　金：山东省医药卫生"九五"攻关项目资助

摘　　要：[目的 ]了解不同人群非胰岛素依赖型糖尿病 (NIDDM)的危险因素 ,为该病适宜的社区干预对策与措施的制订提供科学依据。 [方法 ]1 996～ 1 998年以同一方法对城市 (济南市、滨州市 ) 1 1 5例、农村 (东平、安丘、莘县、长清县 ) 1 0 9例、沿海 (日照、长岛、威海、莱州市 ) 1 0 1例NIDDM患者分别进行 1∶2配比病例对照研究。 [结果 ]糖尿病家族史、体重超重、高血压为三人群NIDDM共有的危险因素 ,但作用强度各异 ,合计人群病因分值 (PARP )分别为5 8 5 2 %、6 5 91 %、6 3 5 8% ;低体力活动为城市特有的危险因素 (OR =1 6 88,PARP =2 8 31 % ) ,喜荤食为农村特有的危险因素 ( OR =2 473,PARP =1 7 78% ) ,喜素食为沿海人群的保护因素 ( OR =0 445 ,PARP =-2 0 5 2 % )。 [结论 ]应针对不同人群的共有与特有的危险因素制订NIDDM的社区干预对策与措施。Objective]To understand the risk factors of non-insulin dependent diabetes mellitus(NIDDM) among different population groups,so as to provide scientific foundation for formulating and implementing community intervention program of the disease.[Methods]Three 1∶2 matched case-control studies of 115 cases in urban Jinan and Binzhou, 109 cases in rural Dongping, Anqiu, Shenxian and Changqing counties and 101 cases in coastal Rizhao, Changdao, Weihai and Laizhou cities were conducted by the same criteria and compared during 1996 to 1998. [Results]Family history of diabetes, overweight,hypertension were the common risk factors of these three population groups, and their association strengths were quite different, the total population etiological fractions (PARP) of the three risk factors for urban, rural and coastal areas were 58.52%,65.91% and 63.58% respectively. Besides the three common risk factors, low physical activity was the special risk factor in urban population (OR=1.688,PARP=28.31%),favor of meat diet was the special risk factor in rural population (OR=2.473,PARP=17.78%), and favor of vegetable diet was the protective factor in coastal population (OR=0.445,PARP=-20.52%).[Conclusions]Community NIDDM intervention program should be proposed and implemented according to the common and special risk factors of different population groups.

关 键 词：糖尿病 危险因素 病例对照 不同人群 NIDDM 

分 类 号：R587.1[医药卫生—内分泌]