超声三维斑点追踪成像评价心肌梗死患者左心室整体收缩功能的研究  

Quantitative evaluation of left ventricular global systolic function in patients with myocardial infarction by three-dimensional speckle tracking echocardiography

作　　者：王丁[1] 邓又斌[1] 黄润青[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声科,武汉430030

出　　处：《中华超声影像学杂志》2012年第11期921-925,共5页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金（81271581）

摘　　要：目的应用超声三维斑点追踪技术评价心肌梗死患者的左室整体应变特征及与左室整体收缩功能的相关性。方法使用三维斑点追踪技术对24例心肌梗死患者及20例正常人进行心肌运动分析，测量左室射血分数（LVEF），左室整体纵向、圆周、径向及面积收缩期峰值应变，并比较心肌梗死组与正常组之间的各应变指标变化情况及与LVEF的相关性。结果三维斑点追踪技术测得心肌梗死患者的LVEF及各整体心肌应变参数均较正常组减低（P〈0．05）。心肌梗死组左室整体纵向、圆周、径向及面积收缩期峰值应变与LVEF的相关系数分别为-0．626、-0．770、0．772和-0．748（P〈0．U1）。Bland—Altman分析显示应变测值在心肌梗死组和正常组均有良好的-致性。结论三维斑点追踪技术可通过测量心肌应变无创、客观地评价左室整体收缩功能，为评估左室收缩功能提供-种新方法。Objective To evaluate the value and characteristics of left ventricular global systolic strain and its relation to the left ventricular global systolic function in patients with myocardial infarction（MI） by three-dimensional speckle tracking echocardiography （3DSTI）. Methods In 24 patient subjects and 20 control subjects, the myocardial motion was tracking by 3D-STI, left ventricular ejection fraction （LVEF）, and global longitudinal peak systolic strain （LVGLS）, global circular peak systolic strain （LVGCS）, global radial peak systolic strain（LVGRS）,global area peak systolic strain（LVGAS） were measured. The values were compared between the two groups, the correlations between LVEF and LVGLS, LVGCS, LVGRS, LVGAS were analyzed respectively. Results （1）There was significant difference of each index about LVEF and global strain between normal group and MI group （all P〈0. 05）. （2）The correlations among LVEF and LVGLS,LVGCS,LVGRS,LVGAS were found （ r = - 0. 626, - 0. 770,0. 772, - 0. 748 respectively, P〈0.01 for all）. （3） Bland-Airman analysis showed there were good agreements in both patients with MI and control subjects. Conclusions 3D-STI could be applied non-invisibly and objective to assess alteration of myocardial global systolic function by accurately measuring strain. Therefore, 3D-STI appears to be a reliable and useful tool to estimate the left ventricular systolic function of MI.

关 键 词：超声心动描记术 心肌梗死 心室功能 左 三维斑点追踪成像 

分 类 号：R445.1[医药卫生—影像医学与核医学]