骨科胫骨平台骨折术后应用地佐辛镇痛的疗效观察  

An Observation on the Curative Effect of Fracture of Tibial Plateau Patients after Application of Dezocine Analgesic

作　　者：宋建治[1] 肖少雄[1] 徐礼森[1] 

机构地区：[1]湖北省武汉市第一医院骨科,湖北武汉430022

出　　处：《药物生物技术》2012年第6期533-534,556,共3页Pharmaceutical Biotechnology

摘　　要：观察地佐辛用于骨科胫骨平台骨折术后的镇痛疗效及安全性。骨科胫骨平台骨折患者120例随机均分成以下两组;治疗组(60例)和对照组(60例)。治疗组患者术后应用地佐辛静脉镇痛,对照组患者术后应用芬太尼静脉镇痛。采用视觉模拟评分(VAS)、镇静评分(Ramsay)评分标准,比较两组患者的术后镇痛效果和不良反应发生率。治疗组与对照组术后VAS评分、Ramsay评分比较差异无统统计学意义(P>0.05),不良反应发生率治疗组明显低于对照组,两组间比较有统计学差异(P<0.05)。骨科胫骨平台骨折术后应用地佐辛具有良好的镇痛效果而副作用明显减少,值得胫骨平台骨折患者术后镇痛临床推广。Observation on dezocine effect of used for fracture of tibial plateau in postoperative analgesia of efficacy and safety. Frac- ture of tibial plateau in 120 patients who were divided into the following two groups （ n = 60）, the treatment group（ in 60 cases ） and the control group （ in 60 cases was observed）. The treatment group patients used dezocine intravenous analgesia while the control group patients used intravenous analgesia with fentanyl. The two groups of patients with postoperative analgesia and the incidence of adverse reactions in choosing the visual analogue scale（VAS） and the sedation score（Ramsay） evaluation standards were compared. The treatment group and the control group after operation in VAS score and Ramsay score had no significant difference in statistic （P 〉0.05 ）. The incidence rate of adverse reaction in treatment group was significantly lower than that in the control group. Compared with each other, there was significant difference in statistic （ P 〈 0.05 ）. Fracture of tibial plateau after using dezocine displayed a good analgesic effect. The side effects were significantly reduced. It is worthy of clinical promotion after fracture of tibial platean in patients with postoperative analgesia.

关 键 词：地位辛 芬太尼 术后镇痛 胫骨平台骨折 

分 类 号：R86[医药卫生—临床医学]