老年股骨骨折患者术前雾化吸入硝酸甘油对氧分压的影响  

The effect of nebulized nitroglycerin inhalation to the partial pressure of oxygen in the elder patients with femoral fracture before operation

作　　者：顾正峰[1] 辛莲[1] 高宏[1] 路通[2] 王志萍[1] 

机构地区：[1]南京医科大学附属无锡市人民医院麻醉科,江苏省无锡市214023 [2]南京医科大学附属无锡市人民医院骨科,江苏省无锡市214023

出　　处：《实用医学杂志》2012年第24期4071-4073,共3页The Journal of Practical Medicine

基　　金：南京医科大学面上项目(编号:08NMUMO94)

摘　　要：目的:观察老年股骨患者手术前雾化吸入硝酸甘油后对氧分压的影响。方法:择年龄65岁以上股骨骨折拟行手术治疗的老年患者40例,随机均分为两组。入院后患者吸氧、抗炎、肺功能锻炼、骨折制动及消肿等治疗。对照组以生理盐水雾化吸入,观察组以硝酸甘油雾化吸入,吸入时监测BP、HR、ECG和SpO2。分别于入院时、吸入治疗后行血气分析,观察氧分压的变化。结果:两组患者的氧分压均得到不同程度的提高,硝酸甘油组与生理盐水组比较差异有统计学意义(P<0.05)。结论:硝酸甘油雾化吸入可以更好地改善老年骨折患者手术前的氧分压。Objective To observe the effect of nebulized nitroglycerin inhalation to the partial pressure of oxygen in the elder patients with femoral fracture before operation. Methods 40 patients more than 65 years old planned to receive femoral fracture intern fixation were selected and randomly divided into two groups. The patients were treated by routine oxygen inhalation, anti-inflammation, functional exercise of lung, fracture brake and detumescenece after admission. The controll group were inhaled nebulized normal saline, while the observed group were inhaled nebulized nitroglycerin. The BP, HR, ECG and SpO2 were monitored during the inhalation. The arterial blood gas was analyzed and the change of partial pressure of oxygen was compared between admission and after inhalation. Results The partial pressure of oxygen in the two groups were both increased after inhalation, which was significantly higher level in the nitroglycerin group than that in the normal saline group （P 〈 0.05）. Conclusion Nebulized nitroglycerin inhalation may better improve the partial pressure of oxygen in the elder patients with femoral fracture before operation.

关 键 词：硝酸甘油 雾化吸入 老年患者 

分 类 号：R683[医药卫生—骨科学]