绍兴市区学龄前哮喘儿童变应原调查  

Allergen survey on preschool children with asthma in Shaoxing city

作　　者：倪铁钧[1,2] 杨明峰[1,2] 冯一[1,2] 

机构地区：[1]浙江省绍兴市人民医院分子医学中心 [2]浙江大学绍兴医院,浙江绍兴312000

出　　处：《中国卫生检验杂志》2012年第11期2764-2765,2770,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解绍兴市区学龄前哮喘儿童(≤6岁)常见的变应原分布。方法:选择2009年1月-2011年12月期间在小儿内科住院确诊哮喘的学龄前儿童87例,采用德国敏筛变应原检测系统以免疫印迹法定量检测患儿血清变应原特异性抗体水平。结果:学龄前哮喘儿童1种以上变应原阳性率77.0%,2种以上变应原阳性率36.8%;吸入性变应原主要以户尘螨、屋尘、菌霉素为主,食物性变应原以牛奶、羊肉为主;3岁～4岁儿童户尘螨和牛奶阳性率明显高于≤2岁和5岁～6岁儿童,5岁～6岁儿童菌霉素阳性率明显高于≤4岁儿童。结论:绍兴市区学龄前哮喘儿童约77.0%为过敏性哮喘,应当及早查出致敏原,并有针对性的进行预防。Objective：To understand the allergen distribution in preschool children（≤6 years） with asthma in Shaoxing city.Methods： 87 cases of preschool children were selected for serum allergen specific antibody detection by western blot,who were diagnosed as asthma in department of Pediatrics of Shaoxing People′s Hospital from January 2009 to December 2011.Results： The positive rate of more than one kinds of allergens in preschool children with asthma was 77.0%,two or more than two kinds was 36.8%;the main inhaled allergens were household dust mites,house dust and mycomycin,food allergens were milk and mutton;the positive rates of household dust mites and milk allergy in 3 to 4 years old children were significantly higher those of children ≤ 2 years and 5 to 6 years old children,the positive rate of mycomycin in 5 to 6 years old children was significantly higher than that in children aged ≤4.Conclusion： About 77.0% of preschool children with asthma in Shaoxing city is allergic asthma,allergens should be identified early for targeted prevention.

关 键 词：儿童 哮喘 变应原 

分 类 号：R562.25[医药卫生—呼吸系统]