Ir-Catalyzed Enantioselective Hydrogenation of 2H-1,4-Benzoxazines with a Chiral 1,2,3,4- Tetrahydro-l-naphthylamine Derived Phosphine-aminophosphine Ligand  

作　　者：胡娟 王道永 郑卓 胡向平 

机构地区：[1]Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian,Liaoning 116023,China

出　　处：《Chinese Journal of Chemistry》2012年第11期2664-2668,共5页中国化学（英文版）

摘　　要：Unsymmetrical hybrid chiral phosphine-aminophosphine ligand derived from 1,2,3,4-tetrahydro-l-naphthyl- amine has been found to be highly efficient in the Ir-catalyzed asymmetric hydrogenation of various 3-aryl-2H-1,4-benzoxazines, providing good enantioselectivities （up to 95% ee） and high catalytic activity （S/C up to 5000）.Unsymmetrical hybrid chiral phosphine-aminophosphine ligand derived from 1,2,3,4-tetrahydro-l-naphthyl- amine has been found to be highly efficient in the Ir-catalyzed asymmetric hydrogenation of various 3-aryl-2H-1,4-benzoxazines, providing good enantioselectivities （up to 95% ee） and high catalytic activity （S/C up to 5000）.

关 键 词：asymmetric catalysis hydrogenation iridium 2H- 1 4-benzoxazine phosphine-aminophosphine ligand 

分 类 号：TQ031.4[化学工程] O643.36[理学—物理化学]