50例鼻咽结核的诊治分析  

Pathogeny and treatment of 50 nasopharyngeal tuberculosis cases

作　　者：简奕娈[1] 刘宝瑛[1] 郭丽霞[1] 孔少颜[1] 苏肖敏[1] 卢春丽[1] 

机构地区：[1]广州市胸科医院五官科,广州510095

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第24期1138-1140,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:分析鼻咽结核的临床表现及诊疗特点,为提高鼻咽结核的临床诊断率提供科学依据。方法:回顾性分析在广州市胸科医院就诊并确诊为鼻咽结核的50例患者的临床资料。50例患者均采用3HRZS(E)/9HR(E)方案抗结核治疗1年,局部用异烟肼、利福平、链霉素的针剂联合喷鼻3个月。结果:全部患者治疗期间没有出现耐药现象,全部完成1年的疗程后治愈并在停药后随访2年均无复发。结论:鼻咽结核较少见,临床表现不典型,极易误诊,充分了解发病的成因及发病初期鼻咽镜下的临床表现及特点,并及时做活检组织病理检查是诊断的关键,从而明确诊断并给予正规的抗结核治疗。Objective：To analyze the clinical characters and treatment of nasopharyngeal tuberculosis, and to provide a scientific basis for improving clinical diagnosis of nasopharyngeal tuberculosis. Method： The clinical ma- terials of 50 patients diagnosed as nasopharyngeal tuberculosis in Guangzhou Chest Hospital were reviewed and an- alyzed. All the 50 patients were given regular antituberculosis treatment with 3HRZS（E）/9HR（E） for one year, and were treated through nasal spray with combination medication of isoniazid, rifampicin and streptomycin injec- tion solution for 3 months. Result： All patients were cured through regular antituberculosis treatment for one year, and no recrudescence cases were found in 2 years of follow-up. Conclusion： Nasopharyngeal tuberculosis is rare and the clinical manifestation is atypical. It is extremely easy to cause clinical misdiagnosis. A full understanding of the pathogenesis, timely clinical characters under nasopharyngoscope and histopathological examination results are the keys to diagnosis, and to giving regular antituberculosis treatment to obtain satisfactory curative effect.

关 键 词：结核 鼻咽 诊断 治疗 

分 类 号：R766.3[医药卫生—耳鼻咽喉科]