复方玄驹胶囊联合万艾可治疗万艾可渐进性失效勃起功能障碍的临床观察  

Combination of Compound Xuanju Capsule and sildenafil for erectile dysfunction that progressively fails to respond to sildenafil

作　　者：陈波特[1,2] 杨槐[1] 吴实坚[1] 

机构地区：[1]广州军区广州总医院泌尿外科,广东广州510010 [2]广州中医药大学,广东广州510405

出　　处：《中华男科学杂志》2012年第12期1101-1104,共4页National Journal of Andrology

摘　　要：目的:探讨复方玄驹胶囊联合万艾可治疗万艾可渐进性失效勃起功能障碍(ED)的临床疗效。方法:将符合万艾可渐进性失效ED诊断标准的36例患者随机分成两组,每组各18例。其中治疗组给予复方玄驹胶囊(口服,2粒/次,3次/日)和万艾可50 mg(性生活前1 h口服)口服;对照组单纯口服万艾可100 mg(性生活前1 h口服)。两组性生活频率1～2次/周,观察期2个月,对用药前后患者国际勃起功能评分(IIEF-5)及TSS伴侣评分进行对比分析。结果:两组每次使用万艾可对勃起功能改善的有效率比较,治疗组总有效率94.44%,对照组88.89%,两组对比差异无显著性意义(P>0.05)。IIEF-5评分治疗组治疗前后分别为(13.166 7±3.601 5)和(20.888 9±3.833 1),而对照组治疗前后分别为(13.055 6±2775 4)和(18.777 8±4.008 2),每组治疗前后对比差异有显著性意义(P<0.05);治疗后两组IIEF-5评分及TSS伴侣评分比较,治疗组的效果均比对照组好,且差异具有显著性意义(P<0.05)。结论:复方玄驹胶囊联合万艾可治疗万艾可渐进性失效ED疗效显著。Objective： To explore the clinical effects of Compound Xuanju Capsule （CXC） combined with sildenafil on erectile dysfunction （ED） that progressively fails to respond to sildenafil. Methods： Totally, 36 ED patients who progressively failed to re- spond to sildenafil were randomly divided into a trial and a control group of equal number, the former treated with oral CXC at 3 g tid plus sildenafil at 50 mg an hour before sexual activity, while the latter with sildenafil alone at 100 mg an hour before sexual activity. After 2 months of treatment, we compared the patients scores on IIEF-5 and their partners scores on Treatment Satisfaction Scale （TSS） between the two groups. Results ： The total rate of erectile function improvement was 94.44% in the trial and 88.89% in the control group （P 〉0.05）. The IIEF-5 score was 20. 888 9±3. 833 1 in the former and 18. 777 8±4. 008 2 in the latter after treat- ment, significantly higher than 13. 166 7 ±3. 601 5 and 13. 055 6± 2. 775 4 before treatment （P 〈0.05）. The post-treatment IIEF-5 scores of the patients and the TSS scores of their partners were markedly higher in the trial than in the control group （P 〈 0. 05 ）. Conclusion： Compound Xuanju Capsule combined with sildenafil is effective for erectile dysfunction that progressively fails to respond to sildenafil.

关 键 词：复方玄驹胶囊 万艾可 勃起功能障碍 

分 类 号：R698.1[医药卫生—泌尿科学]