养精胶囊联合小剂量他达拉非治疗功能性不射精临床观察  

Yangjing Capsule plus low-dose tadalafil for functional anejaculation

作　　者：金保方[1,2,3] 张华俊[1] 张新东[1,2] 孙大林[1] 高永金[1] 夏国守[1,2] 徐福松[1,2] 夏欣一[4] 

机构地区：[1]南京中医药大学男科学研究所,江苏南京210046 [2]南京中医药大学第三附属医院男科,江苏南京210001 [3]江苏省人民医院临床生殖中心,江苏南京210036 [4]南京军区南京总医院男科,江苏南京210002

出　　处：《中华男科学杂志》2012年第12期1140-1142,共3页National Journal of Andrology

基　　金："973"国家重点基础研究发展计划课题基金(2010CB530401);国家自然科学基金(81273760);江苏省中医药管理局康缘中医药科技创新基金项目计划基金(HZ0807KY)~~

摘　　要：目的:探索功能性不射精的有效治疗方法。方法:55例患者随机分为治疗组30例和对照组25例。治疗组养精胶囊,5粒,每日3次;他达拉非5 mg,隔日1次,睡前1 h服用;结合性刺激,减少性交次数,戒除手淫。对照组给予麻黄素片25 mg,睡前口服。两组治疗后1～3个月观察疗效。结果:治疗组30例患者,痊愈11例,显效8例,好转6例,无效5例;2例治疗期间,女方怀孕,总有效率为83.34%。对照组25例患者,痊愈4例,显效3例,好转3例,无效15例,总有效率40.00%。两组经χ2检验,P<0.05,有统计学意义。结论:应用养精胶囊联合小剂量他达拉非是治疗功能性不射精安全有效的可行性疗法。Objective： To search for an effective therapy for functional anejaculation （AE）. Methods ： Fifty-five AE patients were randomized into a treatment group （n = 30） and a control group （n = 25 ）, the former treated with Yangjing Capsule （once 5 pills, tid） and low-dose tadalafil （5 mg, qd alt, 1 h before bedtime）, while the latter with oral ephedrine （25 mg before bedtime）. Meanwhile, the patients were advised to expose themselves to sexual stimulation, reduce the frequency of sexual intercourses and quit masturbation. The medication lasted 1 - 3 months, followed by observation of the therapeutic effects. Results： The total effectiveness rate was 83.34% in the treatment group, 11 cases cured, 8 obviously improved, 6 improved and 5 unimproved, significantly higher than 40.00% in the control group, 4 cases cured, 3 obviously improved, 3 improved and 15 unimproved （ P 〈 0.05 ）. Conclusion ： Yangiing Capsule plus low-dose tadalafil is safe and effective for the treatment of functional anejaculation.

关 键 词：功能性不射精 他达拉非 养精胶囊 性生活指导 

分 类 号：R698[医药卫生—泌尿科学] R45[医药卫生—外科学]