AECOPD合并2型糖尿病患者控制血糖的临床意义  

Clinical value of blood glucose control on patients with acute exacerbation of chronic obstructive pulmonary disease complicated with diabetes B

作　　者：冯洁[1] 戴莉莉[1] 陈晓红[1] 秦斌斌[1] 金烨[1] 沈斌[1] 卢明[1] 

机构地区：[1]上海市第二人民医院,上海200011

出　　处：《临床肺科杂志》2013年第1期47-48,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察血糖控制对AECOPD合并2型糖尿病的影响。方法 82例AECOPD合并2型糖尿病患者随机分为治疗组(42例)和对照组(40例)。治疗组使用胰岛素严格控制血糖在正常范围,对照组使用口服降糖药血糖控制可高于正常范围,分析治疗前后血清CRP、WBC总数、ESR变化,肺功能变化和病程。结果两组治疗后均能降低血清CRP、WBC总数、ESR,改善肺功能,并且治疗组优于对照组,P<0.05。在减少住院天数方面治疗组优于对照组,P<0.05。结论严格的血糖控制对AECOPD合并糖尿病患者感染控制,肺功能改善,缩短病程十分重要。Objective To observe the effect of blood glucose control on patients with cute exacerbation of chronic obstructive pulmonary disease （AECOPD） complicated with diabetes B. Methods 82 AECOPD patients complicated with diabetes B were randomly divided into the treatment group （ n = 42） and the control group （ n = 40 ）. In the treatment group, the study used insulin to strictly control the blood glucose under normal range, and the control group were given antidiabetic drugs orally to keep the blood glucose higher than normal range. The changes of CRP, WBC and ESR in serum and lung function were analyzed before and after the treatment. Results The levels of CRP, WBC and ESR and lung function in the two groups were improved after the treatment, and those in the treatment group was more pronounced than in the control group （P 〈 0. 05 ）. Besides, the average duration of hospital stay in the treatment group was shorter than in the controls （ P 〈 0. 05 ）. Conclusion It is important to strictly control the blood glucose in AECOPD patients complicated with diabetes B for the improvement of lung function and for the shortening duration of hospital stay.

关 键 词：慢性阻塞性肺疾病急性加重期 2型糖尿病 C-反应蛋白 肺功能 

分 类 号：R587.1[医药卫生—内分泌]