法舒地尔在慢性肺源性心脏病患者中的临床疗效  

Clinical effect of fasudil in the treatment of patients with chronic pulmonary heart disease

作　　者：仇爱民[1] 祁风亮 陶章[1] 张海林[1] 

机构地区：[1]盐城市第三人民医院呼吸内科,江苏盐城224001

出　　处：《临床肺科杂志》2013年第1期59-60,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察法舒地尔对慢性肺源性心脏病患者的治疗作用及临床疗效。方法选取住院的慢性肺源性心脏病患者60例,随机分为观察组和对照组各30例,两组患者均给予适当的抗生素抗感染,低流量吸氧,通畅气道,控制心力衰竭等治疗。观察组患者在此基础上加用法舒地尔注射液30 mg溶于0.9%氯化钠注射液100 ml,静脉滴注,2次/d,疗程均为15天。比较两组患者治疗前后的临床症状、动脉血气及超声心动图指标的改善情况。结果观察组疗效优于对照组(P<0.05);观察组治疗后血气分析、各项超声心动图指标与对照组比较差异均有统计学意义(P<0.05)。结论法舒地尔注射液治疗慢性肺源性心脏病疗效显著,值得临床推广应用。Objective To observe the clinical and curative effect of fasudil in the treatment of patients with chronic pulmonary heart disease. Methods 60 patients were randomly and evenly divided into the observation group and the control group, and the two groups were both given appropriate antibiotics, low flow oxygen, airway patency, and heart failure control treatment. Additionally, the observation group were intravenously dripped 100 ml of 0.9% sodium with 30 fasudil dissolved twice a day for 15 days. The clinical symptoms, arterial blood gases and ultrasonic cardiogram indexes were compared between the two groups before and after the treatment. Results The improvement of the blood gases, ultrasonic cardiogram indexes, and clinical symptoms after the treatment were more pronounced in the observation group than in the control group （ P 〈 0. 05 ）. Conclusion The curative effect of fasudil injection in the treatment of chronic pulmonary heart disease is remarkable and it＇s worth to be applied in clinical application.

关 键 词：法舒地尔 慢性肺源性心脏病 疗效 动脉血气分析 超声心动图 

分 类 号：R541.5[医药卫生—心血管疾病]