2型糖尿病患者IMT、FFA水平变化及临床意义  

The level change and clinical significance of FFA and IMT in type 2 diabetes

作　　者：虞美珍 黄翯[2] 

机构地区：[1]浙江省义乌市中医医院内二科,浙江义乌322000 [2]浙江大学医学院附属邵逸夫医院心内科,浙江杭州310058

出　　处：《中国现代医生》2012年第36期18-20,共3页China Modern Doctor

基　　金：国家自然科学基金(81000064)

摘　　要：目的探讨2型糖尿病患者颈动脉内膜中层厚度(IMT)与游离脂肪酸(FFA)水平变化及临床意义。方法选取63例2型糖尿病患者,另选取60例同期健康体检者,分为A、B两组,A组为2型糖尿病组,B组为健康对照组。比较两组血清游离脂肪酸、颈动脉内膜中层厚度以及血糖血脂水平。结果 2型糖尿病组血清FFA水平为(562.68±58.54)μmol/L,IMT为(1.10±0.23)mm,明显高于健康对照组(354.23±45.87)μmol/L,(0.69±0.12)mm,P均<0.05,差异具有统计学意义;2型糖尿病组空腹血糖水平为(10.80±2.99)mmol/L,明显高于健康对照组(4.74±0.90)mmol/L(P<0.05),且A组TC、TG、LDL、HDL水平较B组均有升高(P<0.05)。结论 2型糖尿病患者血清游离脂肪酸水平升高与颈动脉内膜中层增厚相关。Objective To explore the level change and clinical significance of FFA and IMT in type 2 diabetes. Methods Serum level of FFA, carotid IMT, the level of serum lipid and blood glucose were detected in 63 type 2 diabetes mellitus patients （Group A） and 60 healthy controls （Group B）. Results In the type 2 diabetes mellitus group, serum levels of FFA and IMT were, （562.68±58.54） μmol/L and （1.10±0.23）mm, respectively, which were higher than those in healthy control group （354.23±45.87） μmol/L and （0.69＋0.12） mm respectively, with significantly difference （P 〈 0.05）. The level of serum glucose in type 2 diabetes mellitus group was （10.80±2.99） mmol/L, which is higher than it in healthy control group （4.74±0.90）mmol/L （P 〈 0.05）. And there was significant difference between Group A and Group B in the levels of TC, TG, LDL, HDL （P 〈 0.05）. Conelusion Serum level of FFA is associated with IMT in type 2 diabetes mellitus.

关 键 词：颈动脉 2型糖尿病 游离脂肪酸 IMT 

分 类 号：R587.2[医药卫生—内分泌]