局灶型纵隔Castleman病5例手术治疗效果观察  

Surgical treatment of mediastinal localized Castleman' s disease:5 cases report

作　　者：张正华[1] 魏大中[1] 范军[1] 柯立[1] 梅新宇[1] 

机构地区：[1]安徽医科大学附属省立医院胸外科,合肥230001

出　　处：《疑难病杂志》2012年第12期924-925,共2页Chinese Journal of Difficult and Complicated Cases

摘　　要：目的探讨以肺门及纵隔肿块为表现的局灶型纵隔Castleman病的临床特点、诊断及外科治疗效果。方法回顾性分析5例局灶型纵隔Castleman病患者的病历资料及诊疗情况,总结其临床表现、外科诊疗和预后。结果 5例Castleman患者中,男1例、女4例,年龄16～30岁。行开胸手术4例,胸腔镜手术1例,病灶位于右肺门、左前纵隔、左后纵隔、右前纵隔和右后纵隔各1例。病理分型均为透明血管型。行开胸手术为左侧2例、右侧2例,行右侧胸腔镜手术1例,均行纵隔内肿瘤完整切除。随访5～110个月患者均生存、无复发。结论局灶型纵隔Castleman病术前误诊率高,其确诊需依靠病理组织学,手术可行纵隔肿块切除,术后预后较好。Objective To discuss the clinical characteristics,diagnosis and treatment of Castleman＇s disease of local type presenting as hilar and mediastinal mass.Methods Retrospective analysis of 5 mediastinal localized Castleman＇ s disease. Cases records were performed and disease-related clinical manifestations,operations,and prognosis were summarized. Results There were 1 male and 4 female in present study,with the age range from 16 to 30 years old.1 case located at the right hilus of the lung,1 was at left anterior mediastinum,1 was at left posterior mediastinum,1 was at right anterior mediastinum, and 1 was at right posterior mediastinum.All cases were categorized as hyaline vascular type.4 cases were performed open chest operation,lcsae underwent VATS.No recurrence was found in all cases in the 5～110 months follow-up.Conclusion The rate of misdiagnosis of mediastinal localized Castleman＇ s disease is high before operation.Accurate diagnosis relies on histo-pathological.differentiation.Surgical removals of mediastinal masses were recommended for treatment,prognosis was satisfied after surgery.

关 键 词：CASTLEMAN病 诊断 手术 

分 类 号：R655[医药卫生—外科学]