肝细胞表达的免疫相关分子与肝脏疾病  

Expression of immune molecules in hepatocytes and their roles in liver diseases

作　　者：刘敏[1] 王群兴[1] 杨东亮[2] 

机构地区：[1]三峡大学第一临床医学院宜昌市中心人民医院检验科,宜昌443003 [2]华中科技大学同济医学院附属协和医院感染性疾病科,武汉430022

出　　处：《免疫学杂志》2013年第1期78-81,共4页Immunological Journal

摘　　要：以往对于肝脏免疫的研究主要集中于非实质细胞如T细胞、DC、KC和窦状内皮细胞等,而对肝细胞本身的研究相对较少。目前的研究发现肝细胞在被刺激或者微生物侵袭后会表达一系列免疫活性物质参与机体的免疫应答,现就肝细胞表达的免疫相关分子与肝脏疾病之间的一些相关研究进展做一综述。Most of the former studies on the immune system of the liver had focused on the non-parenchymal cells such as T cells, DC, KC and sinusoidal endothelial cells, but less of studies focused on the hepatocytes itself. Current studies found that after the liver was stimulated or invasion by micro-organisms, the hepatocytes should express a series of immune-active substances to participate in the body＇ s immune response. Now, the paper reviews the advancements of these researches about the expression of the immune-related molecules in hepatocytes and the liver diseases.

关 键 词：肝细胞 细胞因子 肝脏疾病 免疫相关分子 天然免疫 

分 类 号：R392.11[医药卫生—免疫学]