腹腔镜手术与开腹手术治疗子宫肌瘤相关指标的Meta分析  

A Meta-Analysis on Related Indexes of Laparoscopic Surgery and Laparotomy in Treatment of Uterine Myoma

作　　者：詹丽丽[1] 洛若愚[1] 倪园园[1] 邹志波[1] 张清[1] 徐翊[1] 

机构地区：[1]武汉大学人民医院,武汉430060

出　　处：《临床误诊误治》2012年第12期55-58,共4页Clinical Misdiagnosis & Mistherapy

摘　　要：目的比较腹腔镜手术及开腹手术治疗子宫肌瘤的安全性及有效性。方法计算机检索Cochrane图书馆、PubMed、EMbase、中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方数据库,选取1995年3月—2012年3月关于腹腔镜手术及开腹手术治疗子宫肌瘤的研究中采用随机对照试验(RCT)的文献,同时手检纳入的参考文献,按纳入排除标准进行RCT文献的筛选,资料提取和质量评价后采用RevMan5.1软件进行Meta分析。结果共纳入8个研究922例,Meta分析结果显示:与开腹手术相比,腹腔镜手术时间较长[加权均属差(WMD)=46.34,95%CI(26.62,66.02),P<0.000 01],术中出血量较少[均属差(MD)=-39.81,95%CI(-50.86,-28.76),P<0.000 01],住院时间较短[WMD=-3.2,95%CI(-3.85,-2.54),P<0.000 01],术后复发率较低[比值比(OR)=0.16,95%CI(0.09,0.29),P<0.000 01]。结论腹腔镜手术与开腹手术相比,疗效相当,手术时间虽较长,但术中出血较少,住院时间短,术后复发率低,安全性更高。Objective To evaluate the efficacy and safety of Laparoscopic surgery and laparotomy in treatment of uterine myoma.Methods Documents in regards to Laparoscopic surgery and laparotomy in treatment of uterine myoma were searched from the Cochrane library,Pubmed,EMbase,CNKI,CbmWin and Wanfang database during March 1995 to March 2012 by randomized controlled trials（RCTs）.At the same time reference documents were involved by hand choice,filtrated by internalization and elimination standards;after selection and quality evaluation the documents of RCTs were performed meta-analysis by the RevMan 5.1 software.Results Eight studies involving 922 patients met the inclusion criteria.The results of meta-analysis showed that laparoscopic surgery had significantly longer operation time than that with laparotomy,less intraoperative bleeding volume,shorter hospital stay and lower postoperative recurrence rates.Conclusion Laparoscopic surgery has similar therapy effect as laparotomy and is safer.But laparoscopic surgery has longer operative time,shorter length of stay and lower postoperative recurrence rate.

关 键 词：子宫肌瘤 腹腔镜手术 开腹手术 META分析 

分 类 号：R713.4[医药卫生—妇产科学]