冠心病患者QT_(LC)间期与心脏危险因素的关系  

Relation ship between QT_(LC) interval and heart risk factors in coronary heart disease patients

作　　者：李潇华[1] 黄佐贵[1] 石伟[1] 杜国伟[1] 余华[1] 殷波[1] 李倩[1] 金海燕[1] 向娟[1] 

机构地区：[1]重庆三峡中心医院百安分院功能科,重庆404000

出　　处：《江苏实用心电学杂志》2012年第4期242-245,共4页Journal of Practical Electrocardiology JS

摘　　要：目的研究冠心病患者QTLC间期值与心脏危险因素的关系。方法对冠心病患者男性300例和女性200例的QTLC与心脏危险因素及其死亡率的关系进行分析。结果 QTLC延长、缩短与高血压和心血管疾病信号及吸烟有关。心血管死亡率QTLC延长5%～10%为0.60%,延长>10%为1.00%;QTLC缩短5%～10%为0.60%,缩短>10%为1.40%。吸烟者死亡率QTLC缩短5%～10%为1.00%,缩短>10%为1.20%;QTLC延长5%～10%为0.60%,延长>10%为1.00%。3例长QT间期和3例短QT间期者植入式心脏复律除颤器(ICD)治疗1年内无恶性心律失常及死亡发生。结论冠心病患者QTLC延长或缩短是预测心血管病死亡率的危险指标,心血管病吸烟者QTLC延长或缩短也是预测心脏死亡率的危险指标。ICD能有效防止恶性室性心律失常的发生率和死亡率。Objective To evaluate the relation ship between value of QTLC interval and heart risk factors in coronary heart disease patients. Methods The association of QTLC interval and heart risk factors and mortality in 39 ～ 75 years coronary heart disease patients of 300 men and 200 women was evaluated. Results Nomogram corrected QT interval（ QTLC ）prolongation and shortened was associated with elevated blood pressure and signs of cardiovascular disease with smoking. QTLC 5% - 10% prolongation total cardiovascular sudden death mortality for 0.60%, over 10% prolongation of sudden death mortality for 1.00% ; QTLC 5% ～ 10% shortened of sudden death for 0.60%, over 10% shortened sudden death 1.40%. 5% 10% shortened QTLCpredicted cardiovascular sudden death in men and women with disease who smoked, mortality for 1.00%, over 10% shortened sudden death mortality for 1.20% ; 5% - 10% prolongation QTLCsudden death mortality for 0.60%, over 10% sudden death mortality for 1.00%. Implanting cardio- verter-defibrillator （ICD） cure three patients prolongation QT interval and three short QT interval in one year during observation without malignant ventrieular arrhythmia and mortality happen. Conclusion For coronary heart disease patients, prolonged and shortened QTLC interval predicts heart mortality and signs of cardiovascular disease. Signs of shortened and prolonged QTLC interval predicts death with heart disease who smoke. Implanting cardioverter-defibrillator could effectively decrease the incidence rate and mortality rate of malignant ventrieular arrhythmia .

关 键 词：冠心病 QTLC间期 心脏 危险因素 

分 类 号：R540.41[医药卫生—心血管疾病]