茵黄合剂与熊去氧胆酸治疗妊娠期肝内胆汁郁积症的疗效比较研究  

Efficacy Comparative Study of Yinhuang Mixture and Ursodeoxycholic Acid on Gestational Intrahepatic Cholestasis

作　　者：张悦[1] 

机构地区：[1]南京医科大学附属南京市妇幼保健院,江苏南京210029

出　　处：《黑龙江医药》2012年第6期840-842,共3页Heilongjiang Medicine journal

摘　　要：目的:观察茵黄合剂与熊去氧胆酸治疗妊娠期肝内胆汁郁积症的疗效比较。方法:将96例病人随机分为2组,一组给予茵黄合剂治疗,一组给予熊去氧胆酸治疗,比较治疗后的疗效指标和分娩结局。结果:在疗效上,茵黄合剂组能降低血甘胆酸值,消除瘙痒,总有效率(显效+有效)达89%,高于熊去氧胆酸组(59%)。在分娩结局上,两组在早产和产后出血率相比无明显差异,但在排除其他因素后因胎窘或ICP为第一指征所做的剖宫产率相比上茵黄合剂组优于熊去氧胆酸组。结论:茵黄合剂治疗妊娠期肝内胆汁郁积症疗效优于熊去氧胆酸。Objective：To study the comparative efficacy of Yinhuang Mixture and ursodeoxyeholie acid on intrahepatie biliary stasis of gestational period. Methods ：96 patients were randomly divided into two groups, one group …… huang mixture, one group was treated with ursodeoxycholic acid, compare tremment efficacy and outcoms of delivery Results： In terms of efficacy, Yinhuang mixture group can reduce biood glycocholic acid value,eliminove itching the total effective rate up to 89% , higher than the ursodeoxycholic acid group （59%）. On birth outcomes ,both groups compared to premature birth, and postpartum hemorrhage, rate was no significant difference,but other factors were excluded because of fetal distress or ICP is the first indication for the cesarean section rate compared to the Yinhuang mixture group superior to ursodeoxycholic acid group. Conclusion： Yanhuang mixture treatment during pregnancy intrahepatic cholestasis efficacy is superior to ursodeoxy- cholic.

关 键 词：妊娠期肝内胆汁郁积症 茵黄合剂 疗效比较 

分 类 号：R714[医药卫生—妇产科学]